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Chemical Structure| 900515-16-4 Chemical Structure| 900515-16-4

Structure of AS-252424
CAS No.: 900515-16-4

Chemical Structure| 900515-16-4

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AS-252424 is a potent PI3Kγ inhibitor with IC50 of 30 nM in a cell-free assay with 30-fold selectivity for PI3Kγ than PI3Kα, and low inhibitory activity towards PI3Kδ/β.

Synonyms: AS-252424

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Product Details of AS-252424

CAS No. :900515-16-4
Formula : C14H8FNO4S
M.W : 305.28
SMILES Code : O=C(NC/1=O)SC1=C/C2=CC=C(C3=CC=C(F)C=C3O)O2
Synonyms :
AS-252424
MDL No. :MFCD12024675

Safety of AS-252424

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P305+P351+P338

Related Pathways of AS-252424

PI3K-AKT

Isoform Comparison

Biological Activity

Target
  • p110γ

    PI3Kγ, IC50:33 nM

  • p110α

    PI3Kα, IC50:935 nM

Protocol

Bio Calculators
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1 mM

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3.28mL

0.66mL

0.33mL

16.38mL

3.28mL

1.64mL

32.76mL

6.55mL

3.28mL

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