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Chemical Structure| 2411382-24-4 Chemical Structure| 2411382-24-4

Structure of ASK1-IN-1
CAS No.: 2411382-24-4

Chemical Structure| 2411382-24-4

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ASK1-IN-1 is a CNS-penetrant ASK1 (apoptosis signal-regulating kinase 1) inhibitor, with good potency (cell IC50=138 nM; Biochemical IC50=21 nM)[1].

Synonyms: CAY10756

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Product Details of ASK1-IN-1

CAS No. :2411382-24-4
Formula : C19H19N9O2
M.W : 405.41
SMILES Code : O=C(NC1=NC(=CC=C1)C2=NN=CN2C(C)C)C3=CN(N=C3OC)C4=NC=CN=C4
Synonyms :
CAY10756
MDL No. :N/A
InChI Key :FTPVMITWJIXRGQ-UHFFFAOYSA-N
Pubchem ID :146027049

Safety of ASK1-IN-1

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of ASK1-IN-1

MAPK

Isoform Comparison

Biological Activity

Description
ASK1-IN-1 is a CNS-penetrant inhibitor of ASK1 (apoptosis signal-regulating kinase 1), exhibiting strong potency with a cellular IC50 of 138 nM and a biochemical IC50 of 21 nM[1].

Protocol

Bio Calculators
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1 mM

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2.47mL

0.49mL

0.25mL

12.33mL

2.47mL

1.23mL

24.67mL

4.93mL

2.47mL

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