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Chemical Structure| 19350-66-4 Chemical Structure| 19350-66-4

Structure of AV-153 free base
CAS No.: 19350-66-4

Chemical Structure| 19350-66-4

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AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity.

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Product Details of AV-153 free base

CAS No. :19350-66-4
Formula : C14H19NO6
M.W : 297.30
SMILES Code : O=C(C1=C(C)NC(C)=C(C(OCC)=O)C1C(O)=O)OCC
MDL No. :MFCD00417306
InChI Key :USGQSNVLGQWBEC-UHFFFAOYSA-N
Pubchem ID :168683

Safety of AV-153 free base

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of AV-153 free base

DNA

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.36mL

0.67mL

0.34mL

16.82mL

3.36mL

1.68mL

33.64mL

6.73mL

3.36mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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