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Chemical Structure| 2787501-83-9 Chemical Structure| 2787501-83-9

Structure of AZD5462
CAS No.: 2787501-83-9

Chemical Structure| 2787501-83-9

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AZD5462 is an RXFP1 modulator for research in heart failure. RXFP1 is a relaxin receptor in humans, belonging to GPCR family 1c, with antifibrotic and anti-inflammatory effects.

4.5 *For Research Use Only !

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Product Details of AZD5462

CAS No. :2787501-83-9
Formula : C30H41FN2O6
M.W : 544.65
SMILES Code : C(NCC1(C)CCC1)(=O)[C@@H]2[C@H](NC(=O)C3=C(OC)C=C(F)C(O[C@H]4CC[C@](C(O)=O)(C)CC4)=C3)[C@@]5(C[C@]2(CC5)[H])[H]
MDL No. :N/A

Safety of AZD5462

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of AZD5462

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05512806 Healthy Participants PHASE1 COMPLETED 2022-11-07 Research Site, Brooklyn, Maryl... More >>and, 21225, United States Less <<
NCT06661733 Renal Impairment PHASE1 RECRUITING 2025-04-28 Research Site, Sofia, 1612, Bu... More >>lgaria Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.84mL

0.37mL

0.18mL

9.18mL

1.84mL

0.92mL

18.36mL

3.67mL

1.84mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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