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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 1011529-10-4 Chemical Structure| 1011529-10-4

Structure of Azvudine
CAS No.: 1011529-10-4

Chemical Structure| 1011529-10-4

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Azvudine (RO-0622) is an effective nucleoside reverse transcriptase inhibitor (NRTI) with antiviral activity against HIV, HBV, and HCV. It exhibits potent inhibition against HIV-1 and HIV-2, with EC50 values of 0.03–6.92 nM and 0.018–0.025 nM, respectively.

Synonyms: RO-0622; FNC

4.5 *For Research Use Only !

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Product Details of Azvudine

CAS No. :1011529-10-4
Formula : C9H11FN6O4
M.W : 286.22
SMILES Code : O=C1N=C(N)C=CN1[C@@H]2O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@@H]2F
Synonyms :
RO-0622; FNC
MDL No. :MFCD26523134

Safety of Azvudine

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H228-H315-H319
Precautionary Statements:P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313
Class:4.1
UN#:1325
Packing Group:

Isoform Comparison

Biological Activity

Target
  • HIV Protease

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05621993 COVID-19 Respiratory Infection RECRUITING 2023-12-31 Department of Respiratory, The... More >> First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, #16766, Jingshi Road, Jinan City, Shandong Province, China, Jinan, Shandong, China Less <<
NCT06006611 COVID-19 ACTIVE_NOT_RECRUITING 2023-10-30 The Fifth Affiliated Hospital ... More >>of Sun Yat-sen University, Zhuhai, Guangdong, 519000, China Less <<
NCT05675748 COVID-19 UNKNOWN 2023-04-15 -

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.49mL

0.70mL

0.35mL

17.47mL

3.49mL

1.75mL

34.94mL

6.99mL

3.49mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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