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Chemical Structure| 2036352-13-1 Chemical Structure| 2036352-13-1

Structure of BAY 1892005
CAS No.: 2036352-13-1

Chemical Structure| 2036352-13-1

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BAY 1892005 is a regulator of p53 protein, acting on p53 aggregates without leading to the reactivation of mutant p53.

4.5 *For Research Use Only !

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Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

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Product Details of BAY 1892005

CAS No. :2036352-13-1
Formula : C11H8ClFN2OS
M.W : 270.71
SMILES Code : O=C(NC1=NC(C2=CC=CC=C2F)=CS1)CCl
MDL No. :N/A

Safety of BAY 1892005

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3261
Packing Group:

Isoform Comparison

Biological Activity

Description
BAY 1892005 modulates the p53 protein, targeting p53 aggregates without reactivating mutant p53 forms. BAY 1892005 inhibits the growth of p53 mutant cell lines Huh7 and H358, showing inhibition concentrations (IC50) of 11.2 μM and 11.1 μM, respectively[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.69mL

0.74mL

0.37mL

18.47mL

3.69mL

1.85mL

36.94mL

7.39mL

3.69mL

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