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Chemical Structure| 2222094-18-8 Chemical Structure| 2222094-18-8

Structure of BC1618
CAS No.: 2222094-18-8

Chemical Structure| 2222094-18-8

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BC1618 is an orally active Fbxo48 inhibitor that promotes mitochondrial fission and autophagy while enhancing liver insulin sensitivity, offering potential applications in metabolic disease research.

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Product Details of BC1618

CAS No. :2222094-18-8
Formula : C24H24F3NO2
M.W : 415.45
SMILES Code : OC(COC1=CC=C(C(F)(F)F)C=C1)CN(CC2=CC=CC=C2)CC3=CC=CC=C3
MDL No. :MFCD33548907
InChI Key :LGTYABNNHILKHF-UHFFFAOYSA-N
Pubchem ID :134417552

Safety of BC1618

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Description
BC1618, an orally active compound that inhibits Fbxo48, induces Ampk-dependent signaling by preventing the degradation of activated pAmpkα mediated by Fbxo48. BC1618 enhances mitochondrial fission, promotes autophagy, and enhances hepatic insulin sensitivity [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.41mL

0.48mL

0.24mL

12.04mL

2.41mL

1.20mL

24.07mL

4.81mL

2.41mL

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