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Chemical Structure| 34539-65-6 Chemical Structure| 34539-65-6

Structure of β,β-Dimethylacrylalkannin
CAS No.: 34539-65-6

Chemical Structure| 34539-65-6

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beta,beta-Dimethylacrylalkannin, a natural product isolated and purified from the roots of Lithospermum erythrorhizon with radical scavenging activity, can be potential therapeutics against tumor cell growth because of its unique DNA damaging abilities additional to enzyme inhibition similar to those of doxorubicin, shows remarkable cytotoxic activity against HT-29, MDA-MB-231 and PC-3 cell lines, comparable or stronger than the other compounds and positive control CPT-11 (CAMPTOSTAR®, irinotecan) with IC50 values in between 0.1uM and 1uM and it has great potential as topo I inhibitors compared to other compounds and CPT-11, with 2-3uM inhibition value, and exhibits inhibitory activities on PTP1B with IC50 values of 0.36±0.08 μMol·L-1.

Synonyms: Arnebin 1

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Product Details of β,β-Dimethylacrylalkannin

CAS No. :34539-65-6
Formula : C21H22O6
M.W : 370.40
SMILES Code : C/C(C)=C\C[C@@H](C(C(C1=C2C(O)=CC=C1O)=O)=CC2=O)OC(/C=C(C)\C)=O
Synonyms :
Arnebin 1
MDL No. :N/A

Safety of β,β-Dimethylacrylalkannin

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H319-H332-H372-H400
Precautionary Statements:P260-P264-P270-P273-P280-P301+P312+P330-P304+P312-P305+P351+P338-P314-P337+P313-P391-P501
Class:9
UN#:3077
Packing Group:

Related Pathways of β,β-Dimethylacrylalkannin

epigenetics

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.70mL

0.54mL

0.27mL

13.50mL

2.70mL

1.35mL

27.00mL

5.40mL

2.70mL

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