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Chemical Structure| 1365655-91-9 Chemical Structure| 1365655-91-9
Chemical Structure| 1365655-91-9

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Boc-NH-PEG2-CH2CH2COOH is a 2-unit PEG derivative with a Boc-protected amino group and a C2-carboxylic acid group. It is used in drug conjugation and peptide synthesis.

4.5 *For Research Use Only !

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Product Citations

Product Citations

Christoff-Tempesta, Ty ; Cho, Yukio ; Kaser, Samuel J ; Uliassi, Linnaea D ; Zuo, Xiaobing ; Hilburg, Shayna L , et al.

Abstract: The dynamic behavior of biological materials is central to their functionality, suggesting that interfacial dynamics could also mediate the activity of che_x005f_x0002_mical events at the surfaces of synthetic materials. Here, we investigate the influence of surface flexibility and hydration on heavy metal remediation by nanostructures self-assembled from small molecules that are decorated with surface-bound chelators in water. We find that incorporating short oli_x005f_x0002_go(ethylene glycol) spacers between the surface and interior domain of self-assembled nanostructures can drastically increase the conformational mobility of surface-bound lead-chelating moieties and promote interaction with surrounding water. In turn, we find the binding affinities of chelators tethered to the most flexible surfaces are more than ten times greater than the least flexible surfaces. Accordingly, nanostructures composed of amphiphiles that give rise to the most dynamic surfaces are capable of remediating thousands of liters of 50 ppb Pb2+-contaminated water with single grams of material. These findings establish interfacial dynamics as a critical design parameter for functional self-assembled nanostructures.

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Product Details of Boc-NH-PEG2-CH2CH2COOH

CAS No. :1365655-91-9
Formula : C12H23NO6
M.W : 277.31
SMILES Code : O=C(O)CCOCCOCCNC(OC(C)(C)C)=O
MDL No. :MFCD22056304
InChI Key :OZMXZVCAXAQCHJ-UHFFFAOYSA-N
Pubchem ID :23591749

Safety of Boc-NH-PEG2-CH2CH2COOH

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338
 

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