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Chemical Structure| 1863952-15-1 Chemical Structure| 1863952-15-1

Structure of CB-5339
CAS No.: 1863952-15-1

Chemical Structure| 1863952-15-1

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CB-5339 is an orally active p97 inhibitor with an IC50 of <30 nM, used in leukemia research.

4.5 *For Research Use Only !

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Product Details of CB-5339

CAS No. :1863952-15-1
Formula : C24H24N6O
M.W : 412.49
SMILES Code : O=C(C1=CC=CC2=C1C=C(C)N2C3=NC(NCC4=CC=CC=C4)=C(CCCN5)C5=N3)N
MDL No. :MFCD34647075

Safety of CB-5339

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of CB-5339

DNA

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT04402541 Acute Myeloid Leukemia, in Rel... More >>apse|Myelodysplastic Syndromes Less << PHASE1 COMPLETED 2023-07-23 USC Norris Comprehensive Cance... More >>r Center, Los Angeles, California, 90033, United States|KU Clinical Research Center, Fairway, Kansas, 66205, United States|Memorial Sloan Kettering Cancer Center, New York, New York, 10021, United States|Weill Cornel Medical Center, New York, New York, 10065, United States|Saint Francis Hospital Cancer Center, Greenville, North Carolina, 29607, United States|Cleveland Clinic, Case Comprehensive Cancer Center, Cleveland, Ohio, 44122, United States|MD Anderson Cancer Cancer, Houston, Texas, 77030, United States|St. Vincent Hospital, Sydney, NSW, Darlinghurst, New South Wales, 2010, Australia|Epworth Healthcare, Melbourne, Victoria, 3002, Australia|Haematology Clinical Trials Unit, Royal Perth Hospital, Perth, Western Australia, 6000, Australia Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.42mL

0.48mL

0.24mL

12.12mL

2.42mL

1.21mL

24.24mL

4.85mL

2.42mL

 

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