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Chemical Structure| 2876918-67-9 Chemical Structure| 2876918-67-9

Structure of CB2R/FAAH modulator-3
CAS No.: 2876918-67-9

Chemical Structure| 2876918-67-9

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CB2R/FAAH modulator-3 is a dual-target modulator acting as a CB2R agonist and FAAH inhibitor, with Ki values of 20.1 nM for CB2R and 67.6 nM for CB1R, and an IC50 of 3.4 μM for FAAH. It is used for research on harmful inflammatory cascades in cancer, neurodegenerative diseases, and COVID-19 infection.

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Product Details of CB2R/FAAH modulator-3

CAS No. :2876918-67-9
Formula : C22H31NO2
M.W : 341.49
SMILES Code : O=C(NC12CC3CC(C2)CC(C3)C1)C4=CC=CC=C4OCCCCC
MDL No. :N/A

Safety of CB2R/FAAH modulator-3

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of CB2R/FAAH modulator-3

GPCR

Isoform Comparison

Biological Activity

Description
Similarly, CB2R/FAAH modulator-3 is characterized as a dual targeting modulator acting as a CB2R agonist and FAAH inhibitor. It exhibits Ki values of 20.1 nM and 67.6 nM for CB2R and CB1R, respectively, and an IC50 value of 3.4 μM for FAAH. CB2R/FAAH modulator-3 also shows potential for use in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.93mL

0.59mL

0.29mL

14.64mL

2.93mL

1.46mL

29.28mL

5.86mL

2.93mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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