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Chemical Structure| 2216764-29-1 Chemical Structure| 2216764-29-1

Structure of CD73-IN-4
CAS No.: 2216764-29-1

Chemical Structure| 2216764-29-1

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CD73-IN-4 is a highly effective and selective CD73 inhibitor with an IC50 of 2.6 nM. It is extensively used in cancer immunology research, enhancing anti-tumor immune responses by blocking adenosine production.

4.5 *For Research Use Only !

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Product Details of CD73-IN-4

CAS No. :2216764-29-1
Formula : C16H23ClN5O7P
M.W : 463.81
SMILES Code : O[C@@H]1[C@H](O)[C@@H](COCP(O)(O)=O)O[C@H]1N2N=CC3=C(NC4CCCC4)N=C(Cl)N=C32
MDL No. :MFCD33548889

Safety of CD73-IN-4

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Isoform Comparison

Biological Activity

Description
CD73-IN-4 is a highly potent and selective methylenephosphonic acid inhibitor of CD73, exhibiting an IC50 value of 2.6 nM against human CD73. It holds promise for cancer immunology research[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.16mL

0.43mL

0.22mL

10.78mL

2.16mL

1.08mL

21.56mL

4.31mL

2.16mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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