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Chemical Structure| 1628416-28-3 Chemical Structure| 1628416-28-3

Structure of CFTR corrector 2
CAS No.: 1628416-28-3

Chemical Structure| 1628416-28-3

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CFTR corrector 2 is a regulator of cystic fibrosis transmembrane conductance regulatory factor (CFTR). CFTR, a chloride channel in the membrane of epithelial cells, is essential for salt and fluid homeostasis.

Synonyms: FDL169

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Product Details of CFTR corrector 2

CAS No. :1628416-28-3
Formula : C27H23FN4O4
M.W : 486.49
SMILES Code : O=C(N(C)C1=CC=C2N=C(C)OC2=C1)CN(N=C(C3=CC=CC(F)=C3)C4=C5C=C(OCC)C=C4)C5=O
Synonyms :
FDL169
MDL No. :MFCD32062823
InChI Key :XRPSUWYWZUQALB-UHFFFAOYSA-N
Pubchem ID :86298861

Safety of CFTR corrector 2

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT02767297 Cystic Fibrosis PHASE1|PHASE2 COMPLETED 2025-10-16 Celerion, Belfast, BT9 6AD, Un... More >>ited Kingdom Less <<
NCT03424252 Cystic Fibrosis PHASE1 COMPLETED 2018-01-15 Quotient Sciences, Nottingham,... More >> NG116JS, United Kingdom Less <<
NCT03527095 Cystic Fibrosis PHASE1 COMPLETED 2018-06-21 Quotient Sciences, Ruddington,... More >> Nottingham, NG11 6JS, United Kingdom Less <<
NCT02680418 Cystic Fibrosis PHASE1 COMPLETED 2025-02-16 Simbec Research Ltd, Merthyr T... More >>ydfil, Wales, CF48 4DR, United Kingdom Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.06mL

0.41mL

0.21mL

10.28mL

2.06mL

1.03mL

20.56mL

4.11mL

2.06mL

References

 

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