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Chemical Structure| 3858-89-7 Chemical Structure| 3858-89-7

Structure of Chloroprocaine HCl
CAS No.: 3858-89-7

Chemical Structure| 3858-89-7

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Chloroprocaine HCl is a local anesthetic during surgical procedures.

Synonyms: 2-Chloroprocaine hydrochloride; Chloroprocaine hydrochloride; Chloroprocaine(hydrochloride)

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Product Details of Chloroprocaine HCl

CAS No. :3858-89-7
Formula : C13H20Cl2N2O2
M.W : 307.22
SMILES Code : O=C(OCCN(CC)CC)C1=CC=C(N)C=C1Cl.[H]Cl
Synonyms :
2-Chloroprocaine hydrochloride; Chloroprocaine hydrochloride; Chloroprocaine(hydrochloride)

Safety of Chloroprocaine HCl

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03715244 - Not yet recruiting December 30, 2021 Germany ... More >> Department of Anesthesiology and Operative Intensive Care Medicine (CCM/CVK), Charité - Universitätsmedizin Berlin Not yet recruiting Berlin, Germany, 10117 Contact: Claudia Spies, MD, Prof.    +49 30 450 55 10 01    claudia.spies@charite.de    Principal Investigator: Claudia Spies, MD, Prof.          Sub-Investigator: Valesca Kipping, MD          Sub-Investigator: Sascha Tafelski, MD          Sub-Investigator: Jürgen Birnbaum, MD          Sub-Investigator: Philipp Pickerodt, MD          Sub-Investigator: Elisa Iwan, MD          Sub-Investigator: Anika Müller, MD Less <<
NCT02726620 Hypotension Not Applicable Active, not recruiting December 31, 2018 United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Less <<
NCT01655277 Quadriceps Muscle Weakness ... More >> Adductor Muscle Weakness Fall Risk Less << Phase 4 Completed - United States, New York ... More >> St. Luke's Roosevelt Hospital New York, New York, United States, 10025 Less <<
NCT02152293 - Completed - France ... More >> Nordic Pharma Paris, France Less <<
NCT03395990 Osteo Arthritis Knee Not Applicable Completed - United States, North Carolina ... More >> Duke University Hospital Durham, North Carolina, United States, 27710 Less <<
NCT02282319 Surgery Ambulatory Phase 4 Recruiting July 2019 Belgium ... More >> University Hospital Antwerp Recruiting Antwerp, Belgium, 2650 Contact: Margaretha Breebaart, MD       margaretha.breebaart@uza.be    Contact: veerle verheyen, nurse    003238214405    veerle.verheyen@uza.be    Sint Augustinus Completed Wilrijk, Belgium, 2610 Less <<
NCT03173326 Knee Arthroscopy ... More >> General Anesthesia Subarachnoid Block Less << Not Applicable Terminated(Staffing changes at... More >> site. No longer feasible at site.) Less << - United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Less <<
NCT00487084 Labor Analges... More >>ia, Epidural Less << Not Applicable Completed - United States, Illinois ... More >> Northwestern University Chicago, Illinois, United States, 60611 Less <<
NCT03365752 Knee Arthroscopy Phase 2 Recruiting September 2019 United States, New York ... More >> Hospital for Special Surgery Recruiting New York, New York, United States, 10021 Contact: David Kim, MD    646-714-6794    kimd@hss.edu Less <<
NCT03428230 Pain, Postoperative Phase 2 Recruiting January 31, 2019 Switzerland ... More >> Department of Anaesthesiology, Clinica Ars Medica Recruiting Gravesano, Switzerland, 6929 Contact: Claudio Camponovo, MD    +41(0)91 611 ext 6211    ccamponovo@arsmedica.ch    Principal Investigator: Claudio Camponovo, MD Less <<
NCT03414359 Surgical Anesthesia, Cesarean ... More >>Section Less << Early Phase 1 Recruiting January 1, 2019 United States, Arkansas ... More >> University of Arkansas for Medical Sciences Recruiting Little Rock, Arkansas, United States, 72205 Contact: Nadir Sharawi, MD    501-319-2622    nelsharawi@uams.edu Less <<
NCT00487084 - Completed - -
NCT02207855 - Completed - United States, Ohio ... More >> Nationwide Children's Hospital Columbus, Ohio, United States, 43205 Less <<
NCT02406703 - Completed - -
NCT02385097 Axillary Nerve Block Phase 3 Completed - Switzerland ... More >> Claudio Camponovo Gravesano, Lugano, Switzerland, CH-6929 Less <<
NCT03038958 Knee Arthroscopy ... More >> Spinal Anesthesia Less << Phase 4 Completed - Belgium ... More >> Braine-l'Alleud Hospital Braine-l'Alleud, Belgium, 1420 CHU Saint-Pierre Brussels Capital Region, Belgium, 1000 Less <<
NCT01719237 Pain Phase 4 Completed - United States, New Mexico ... More >> University of New Mexico Albuquerque, New Mexico, United States, 87106 Less <<
NCT02919072 Unplanned Caesarean Section Phase 3 Recruiting December 2018 Belgium ... More >> UZ Leuven, campus Gasthuisberg Recruiting Leuven, Belgium, 3000 Contact: Marc Van de Velde, MD    0032 (0)16 34 1234 ext 0032    marc.vandevelde@uzleuven.be Less <<
NCT02862912 Adverse Reaction to Spinal Ane... More >>sthetic Maternal Care for Cervical Incompetence Less << Phase 4 Recruiting December 31, 2018 United States, New York ... More >> New York Presbyterian Hospital Recruiting New York, New York, United States, 10032 Contact: Allison Lee, MD       al3196@columbia.edu    Principal Investigator: Richard Smiley, MD Less <<
NCT00845962 Spinal Anesthesia Not Applicable Completed - Canada, Quebec ... More >> St-Luc Hospital CHUM Montreal, Quebec, Canada, H2X 3J4 Less <<
NCT02049255 Pain Phase 4 Completed - Belgium ... More >> Clinique Saint-Luc Bouge Bouge, Namur, Belgium, 5004 Less <<
NCT02481505 Short Duration Lower Limb Surg... More >>ery Via Spinal Anaesthesia Less << Phase 2 Completed - Italy ... More >> Stefano Bonarelli Bologna, Italy, 40136 Less <<
NCT02813382 - Completed - -
NCT03305575 Cervical Incompetence Phase 4 Recruiting October 2018 United States, Massachusetts ... More >> Tufts Medical Center Recruiting Boston, Massachusetts, United States, 02111 Contact: Dan Drzymalski, MD    617-636-6044    ddrzymalski@tuftsmedicalcenter.org    Contact: Alaa Basura, MD    (617) 636-6044    abasura@tuftsmedicalcenter.org Less <<
NCT03324984 Return of Motor and Sensory Bl... More >>ockade Anesthesia, Spinal Decrease Discharge Time Status Post Hemmoriodectomy Less << Phase 2 Withdrawn(IND required for IRB... More >> approval) Less << November 20, 2019 -
NCT03260972 Cesarean Section Complications... More >> Pain Less << Phase 3 Not yet recruiting December 2020 -
NCT02287870 Anesthesia Phase 4 Completed - -
NCT03760718 Cesarean Section Early Phase 1 Not yet recruiting June 30, 2020 -
NCT01909089 Pain Relief During Labour Phase 4 Unknown May 2015 Belgium ... More >> Ghent University Hospital Recruiting Ghent, Belgium, 9000 Contact: Marc Coppens, MD       Marc.Coppens@ugent.be    Principal Investigator: Marc Coppens, MD Less <<
NCT02067806 - Completed - Belgium ... More >> Department of Anesthesiology and Critical Care Medicine-Hospital AZ Sint Jozef Malle, Belgium, 2390 Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.25mL

0.65mL

0.33mL

16.27mL

3.25mL

1.63mL

32.55mL

6.51mL

3.25mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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