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Chemical Structure| 2143917-62-6 Chemical Structure| 2143917-62-6

Structure of Cirtuvivint
CAS No.: 2143917-62-6

Chemical Structure| 2143917-62-6

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Cirtuvivint is a CLK inhibitor that can specifically inhibit the function of CLK proteins.

Synonyms: SM08502

4.5 *For Research Use Only !

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Product Details of Cirtuvivint

CAS No. :2143917-62-6
Formula : C24H25N7O
M.W : 427.50
SMILES Code : O=C(NC1=CC2=C(C=N1)C=CC(C3=CN(C)N=C3)=C2)C4=CC=NC(N5CCN(C)CC5)=C4
Synonyms :
SM08502
MDL No. :MFCD34578253

Safety of Cirtuvivint

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of Cirtuvivint

Hedgehog

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03355066 Solid Tumor, Adult PHASE1 TERMINATED 2022-11-14 Honor Health Research Institut... More >>e, Scottsdale, Arizona, 85258, United States|University of Arizona Cancer Center, Tucson, Arizona, 85724, United States|City of Hope Medical Center, Duarte, California, 91010, United States|UC Davis - Comprehensive Cancer Center, Sacramento, California, 95817, United States|Sarah Cannon Research Institute at HealthONE, Denver, Colorado, 80218, United States|Florida Cancer Specialists, Sarasota, Florida, 34232, United States|Northside Hospital, Atlanta, Georgia, 30342, United States|Dana Farber Cancer Institute, Boston, Massachusetts, 02215, United States|START Midwest, Grand Rapids, Michigan, 49546, United States|Washington University School of Medicine, Saint Louis, Missouri, 63110, United States|Memorial Sloan Kettering Cancer Center, New York, New York, 10065, United States|Duke Cancer Institute, Durham, North Carolina, 27710, United States|Gabrail Cancer Center, Canton, Ohio, 44718, United States|University of Oklahoma Medicine Stephenson Cancer Center, Oklahoma City, Oklahoma, 73104, United States|Vanderbilt University Medical Center, Nashville, Tennessee, 37232, United States|Vanderbilt University, Nashville, Tennessee, 37232, United States|NEXT Oncology, San Antonio, Texas, 78229, United States|UT Health San Antonio - Mays Cancer Center, San Antonio, Texas, 78229, United States|START Mountain Region, West Valley City, Utah, 84119, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.34mL

0.47mL

0.23mL

11.70mL

2.34mL

1.17mL

23.39mL

4.68mL

2.34mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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