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Chemical Structure| 33818-15-4 Chemical Structure| 33818-15-4
Chemical Structure| 33818-15-4

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Citicoline Sodium is an essential component of cell membrane phospholipids. Citicoline (CDP-choline or cytidinediphosphate choline; cytidine 5′-diphosphocholine) is a complex organic molecule composed of ribose, pyrophosphate, cytosine and choline. Citicoline is very water soluble and has a bioavailability of greater than 90%. Citicoline presented no mitogenic and chemotactic effects on hCMEC/D3; however, it significantly increased wound recovery, spheroid sprouting and strongly induced endothelial tube-like structure formation in Matrigel. Citicoline induced the expression of phospho-extracellular-signal regulated kinase (ERK)-1/2. It protects hCMEC/D3 against cell damage/apoptosis. Citicoline induces angiogenesis and improves survival of human brain microvessel endothelial cells through pathways involving p-ERK1/2, and IRS-1.

Synonyms: Citicoline sodium; Cytidine diphosphate-choline sodium; Citicoline Na

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Product Details of Citicoline sodium salt

CAS No. :33818-15-4
Formula : C14H25N4NaO11P2
M.W : 510.31
SMILES Code : O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OCC[N+](C)(C)C)([O-])=O)([O-])=O)N2C(N=C(C=C2)N)=O.[Na+]
Synonyms :
Citicoline sodium; Cytidine diphosphate-choline sodium; Citicoline Na
MDL No. :MFCD00037486

Safety of Citicoline sodium salt

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310
 

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