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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 4205-91-8 Chemical Structure| 4205-91-8

Structure of Clonidine HCl
CAS No.: 4205-91-8

Chemical Structure| 4205-91-8

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Clonidine HCl is a centrally-acting and brain-permeable α2-adrenergic agonist, which can induce a decrease in blood pressure.

Synonyms: Clonidine (hydrochloride); Kapvay; Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-, monohydrochloride

4.5 *For Research Use Only !

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Product Details of Clonidine HCl

CAS No. :4205-91-8
Formula : C9H10Cl3N3
M.W : 266.55
SMILES Code : ClC1=C(NC2=NCCN2)C(Cl)=CC=C1.Cl
Synonyms :
Clonidine (hydrochloride); Kapvay; Benzenamine, 2,6-dichloro-N-2-imidazolidinylidene-, monohydrochloride
MDL No. :MFCD00036705

Safety of Clonidine HCl

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P260-P264-P270-P271-P284-P304+P340-P310-P330-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Clonidine HCl

GPCR

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
Adipose stem cells (ASCs) 10 or 20 μM 72 h To study the effect of Clonidine on ASCs growth factors secretion and expression. Results showed that Clonidine treatment significantly reduced the secretion and expression of HGF, TGF-β1, and VEGF. Stem Cell Res Ther. 2025 Feb 14;16(1):72
Adipose stem cells (ASCs) 10 or 20 μM 48 h To study the effect of Clonidine on ASCs migration and proliferation. Results showed that Clonidine treatment significantly inhibited ASCs migration and proliferation in a dose-dependent manner. Stem Cell Res Ther. 2025 Feb 14;16(1):72

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Rat Neonatal rat model Intrathecal injection 0.03, 0.1, 0.3, 1, 3, 10 mg/kg Single injection To evaluate the analgesic effects and potential spinal toxicity of clonidine. Results showed that intrathecal clonidine did not produce signs of spinal cord toxicity in neonatal rats, even at doses much greater than required for analgesia. Anesth Analg. 2012 Aug;115(2):450-60
Sprague-Dawley rats L5-L6 spinal nerve ligation (SNL) model Intrathecal injection 15 μg/rat Single injection Clonidine alleviated hypersensitivity in SNL rats via GABA receptor-mediated mechanisms and increased spinal GABA and acetylcholine release. Anesthesiology. 2012 Aug;117(2):389-98
Rats Satiated rat model Intra-PVN injection 5, 10, 20 nmol/rat Single injection, observed for 24 hours To evaluate the effect of clonidine on agmatine-induced feeding behavior. Pretreatment with clonidine (5 nmol) significantly potentiated the orexigenic effect of agmatine (5 nmol). Br J Pharmacol. 2011 Sep;164(2b):704-18
Rats L5 and L6 spinal nerve ligation (SNL) model Intrathecal injection 1–15 μg/10 μl Single injection To evaluate the antihypersensitivity effect of clonidine and its cholinergic dependency at different time points after nerve injury. Results showed that nerve injury did not affect cholinergic dependency but time-dependently reduced the efficacy of α2-adrenoceptor-mediated antihypersensitivity. Pain. 2016 Sep;157(9):2024-2032
Mice C57BL/6J mice Intraperitoneal injection 1 mg/kg 2 hours daily on postnatal days 6, 9, and 12 Clonidine attenuated sevoflurane-induced Tau phosphorylation and cognitive impairment via activation of alpha-2 adrenergic receptor. Anesth Analg. 2021 Mar 1;132(3):878-889
Rats Hemorrhagic shock model Subcutaneous injection 150 μg/kg Twice a day for 2 days and one dose in the morning before the experiment. To study the effect of clonidine pre-treatment on hemorrhagic shock-induced endotoxemia and oxidative stress in rats. Results showed that clonidine pre-treatment significantly reduced the production of oxidative stress markers (LOOHs and O2?·) in the gut, liver, and lungs, and decreased endotoxin levels in portal and systemic circulation. Redox Rep. 2012;17(6):246-51

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03174067 Opioid Withdrawal ... More >> Opioid-use Disorder Less << Phase 4 Completed - -
NCT00312416 Ocular Physiology ... More >> Regional Blood Flow Less << Phase 4 Completed - Austria ... More >> Department of Clinical Pharmacology Vienna, Austria, 1090 Less <<
NCT01205204 Full Term Pregnant Patients ... More >> Undergoing Lower Segment Caesarian Section Less << Not Applicable Withdrawn(This study was regis... More >>tered with Clinical Trials.gov by mistake.) Less << November 2011 -
NCT03207022 Brachial Plexus Blockade Not Applicable Completed - -
NCT01963299 Indication for Surgery of the ... More >>Posterior Segment Under Locoregional Anaesthesia Less << Phase 2 Completed - France ... More >> CHU Dijon Dijon, France, 21 Less <<
NCT01507701 Chronic Fatigue Syndrome Not Applicable Completed - Norway ... More >> Oslo University Hospital Rikshospitalet, Dept. of Pediatrics Oslo, Norway, NO-4950 Less <<
NCT01385748 - Completed - -
NCT03057015 Postoperative Pain Phase 4 Recruiting February 28, 2019 United States, Vermont ... More >> University of Vermont Medical Center Recruiting Burlington, Vermont, United States, 05401 Contact: Borzoo Farhang, DO    802-881-9927    borzoo.farhang@uvmhealth.org    Principal Investigator: Borzoo Farhang, DO Less <<
NCT01385748 Oral Mucositis Phase 2 Completed - -
NCT00626977 - Completed - Brazil ... More >> College of Medicine of Botucatu Botucatu, São Paulo, Brazil, 18618970 Less <<
NCT00414921 Attention Deficit Hyperactivit... More >>y Disorder Less << Phase 2 Completed - United States, New York ... More >> University of Rochester Medical Center, Department of Neurology, 919 Westfall Road, Building C Rochester, New York, United States, 14618 United States, Ohio University of Cincinnati, Department of Psychiatry, 231 Albert Sabin Way, M: 0559 Cincinnati, Ohio, United States, 45267-0559 United States, Pennsylvania Western Psychiatric Institute and Clinic, ADD Program, 3811 Ohara Street Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT02249039 Mechanical Ventilation Complic... More >>ation Less << Phase 1 Phase 2 Recruiting June 2019 United States, Maryland ... More >> Johns Hopkins Hospital Recruiting Baltimore, Maryland, United States, 21287 Contact: Sapna R Kudchadkar, MD    410-955-6412    sapna@jhmi.edu    Contact: Pam Melvin, RN    410-955-6412    pam@jhmi.edu Less <<
NCT01112878 Shoulder Arthroscopy ... More >> Knee Arthroscopy Less << Phase 4 Withdrawn(Several studies goin... More >>g on at the same time.) Less << June 2015 United States, California ... More >> Cedars Sinai Medical Center Los Angeles, California, United States, 90048 Less <<
NCT03679052 Shivering Phase 4 Completed - Egypt ... More >> Ibrahim Mamdouh Esmat Heliopolis, Cairo, Egypt, 11361 Less <<
NCT00295308 Opioid-Related Disorders Phase 1 Completed - United States, Maryland ... More >> National Institute on Drug Abuse Baltimore, Maryland, United States, 21224 Less <<
NCT00417443 Postoperative Hyperalgesia Phase 3 Withdrawn - United Kingdom ... More >> Addenbrooke's Hospital Cambridge, Cambridgeshire, United Kingdom, CB1 9YJ Less <<
NCT02404077 - Completed - -
NCT00672347 Postoperative Pain Phase 1 Phase 2 Completed - Brazil ... More >> Santa Casa de Belo Horizonte Hospital Belo Horizonte, Minas Gerais, Brazil Less <<
NCT02151487 Upper Extremity Fracture Phase 3 Completed - United States, Texas ... More >> Parkland Health Hospital System Dallas, Texas, United States, 750390 Less <<
NCT03117140 - Completed - -
NCT00166686 Treatment-Related Cancer Phase 1 Phase 2 Withdrawn(Study was never init... More >>iated) Less << - United States, Texas ... More >> Baylor College of Medicine Houston, Texas, United States, 77030 Less <<
NCT02128451 Amputation Stumps Phase 4 Completed - Egypt ... More >> Faculty of Medicine ,Tanta University. Tanta, Algharbiya, Egypt, 35217 Tanta University Hospitals Tanta, Algharbyia, Egypt, 35217 Less <<
NCT00723190 - Completed - -
NCT00959062 Respiration, Artificial ... More >> Critical Illness Conscious Sedation Deep Sedation Less << Phase 4 Completed - Canada, Ontario ... More >> McMaster Children's Hospital/Hamilton Health Sciences Hamilton, Ontario, Canada, L8n 3Z5 London Health Sciences Centre London, Ontario, Canada Less <<
NCT03770013 Postoperative Pain Not Applicable Not yet recruiting September 1, 2020 -
NCT00723190 Attention Deficit Hyperactivit... More >>y Disorder Less << Phase 3 Completed - -
NCT00349921 - Completed - -
NCT02773602 Postoperative Pain Phase 4 Unknown December 2017 United States, Texas ... More >> Memorial Hermann Hospital Recruiting Houston, Texas, United States, 77030 Contact: EMAD M SORIAL, (M.B; B.CH)    713-550-6186    EMAD.M.SORIAL@UTH.TMC.EDU    Principal Investigator: Samia N Khalil, (M.B; B.CH) Less <<
NCT03117140 Anesthesia, Local Phase 4 Completed - United States, Iowa ... More >> University of Iowa Hospital and Clinics, Ambulatory Surgery Clinic Iowa City, Iowa, United States, 52242 Less <<
NCT02539693 Pilonidal Sinus Not Applicable Recruiting January 2019 Lebanon ... More >> Makassed General Hospital Recruiting Beirut, Lebanon Contact: Zoher Naja, MD    +9611636000 ext 6405    zouhnaja@yahoo.com Less <<
NCT01175668 - Terminated(Based on the planne... More >>d interim analysis results at 50% recruitment, after IRB reviewed the results, further enrollment was stopped.) Less << - -
NCT00349921 Pain Phase 2 Completed - United States, North Carolina ... More >> The Center for Clinical Research, 145 Kimel Park Drive Winston-Salem, North Carolina, United States, 27103 Wake Forest University School of Medicine, Medical Center Boulevard Winston-Salem, North Carolina, United States, 27157-1009 Less <<
NCT02509273 Sedation in Intensive Care Phase 3 Recruiting August 2019 Czechia ... More >> Univerzita Karlova v Praze Recruiting Prague, Czechia, 121 09 Contact: Kristýna Matějková, DiS          Principal Investigator: Pavla Pokorna, MD          Estonia Tallinn Children`s Hospital Recruiting Tallinn, Estonia Contact: Mari-Liis Ilmoja, MD    +372 55573326    mari-liis.ilmoja@lastehaigla.ee    Principal Investigator: Mari-Liis Ilmoja, MD          Germany University of Erlangen-Nürnberg Medical School Recruiting Erlangen, Germany, 91054 Contact: Evelin Muschiol    +49 9131 85-41203    evelin.muschiol@uk-erlangen.de    Principal Investigator: Thomas MK Völkl, MD          Diakonie Neuendettelsau - Cnopf'sche Kinderklinik Nürnberg Recruiting Nürnberg, Germany Contact: Michael Schroth, Prof. Dr. med.    +49 +911 3340 3240    Michael.Schroth@diakonieneuendettelsau.de    Principal Investigator: Michael Schroth, MD PhD          Italy Azienda Ospedaliero Universitaria Policlinico di Bari Not yet recruiting Bari, Italy, 70124 Contact: Manuela Capozza, MD    +390805593329    manuelacapozza26@gmail.com    Principal Investigator: Nicola Laforgia, Prof MD          ARNAS Civico Di Cristina Benfratelli Not yet recruiting Palermo, Italy, 90127 Contact: Giusy Costantino, MD       giusy.costantino.utin@gmail.com    Principal Investigator: Marcello Vitaliti, MD          Bambino Gesù Hospital and Research Institute Recruiting Rome, Italy, 00165 Contact: Alessandra Simonetti, MD       alessandra.simonetti@opbg.net    Principal Investigator: Alessandra Simonetti, MD          Netherlands Erasmus Medical Center Recruiting Rotterdam, Zuid-Holland, Netherlands, 3015 CN Contact: Dick Tibboel, MD Prof    +31 10 703 75 94    d.tibboel@erasmusmc.nl    Principal Investigator: Dick Tibboel, MD Prof          Spain Hospital Universitario 12 de Octubre Recruiting Madrid, Spain, 28041 Contact: Barbara Muñoz Amat, MD    +34 91 390 8372    barbara.munoz@salud.madrid.org    Principal Investigator: Barbara Muñoz Amat, MD          Sweden Karolinska Institutet Recruiting Stockholm, Sweden, 17176 Contact: Peter Larsson, MD, PhD    +46851777269    peter.larsson@karolinska.se    Contact: Johan Fenhammar, MD, PhD    +46851773735    johan.fenhammar@karolinska.se    Principal Investigator: Jonas Berner, MD, PhD Less <<
NCT01075490 Spinal Anesthesia ... More >> Neonates Less << Phase 4 Unknown December 2009 France ... More >> CHU de Montpellier Recruiting Montpellier, France, 34295 Contact: Alain Rochette, MD    (33)467338256    a-rochette@chu-montpellier.fr Less <<
NCT01175668 Neonatal Abstinence Syndrome Not Applicable Terminated(Based on the planne... More >>d interim analysis results at 50% recruitment, after IRB reviewed the results, further enrollment was stopped.) Less << - United States, Massachusetts ... More >> NICU @ Baystate Children's Hospital Springfield, Massachusetts, United States, 01199 Less <<
NCT02239627 Back Pain Not Applicable Terminated(based on interim an... More >>aylsis) Less << - United States, West Virginia ... More >> West Virginia University Hospitals Morgantown, West Virginia, United States, 26505 Less <<
NCT00329511 Hypertension Not Applicable Withdrawn(Feasibility of study... More >>. PI termination) Less << - United States, California ... More >> Long Beach Memorial Medical Center Long Beach, California, United States, 90806 Less <<
NCT00585871 Ventricular Tachycardia Not Applicable Withdrawn(could not recruit) - United States, Iowa ... More >> UIHC Iowa City, Iowa, United States, 52242 Less <<
NCT01597427 Anesthesia Phase 2 Completed - Brazil ... More >> Luiz Fernando dos Reis Falcao Sao Paulo, SP, Brazil, 04024-002 Less <<
NCT00588354 Lumbar and Other Intervertebra... More >>l Disc Disorders With Radiculopathy Less << Not Applicable Terminated(Targeted enrollment... More >> was not reached.) Less << - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT01293149 Other Reconstructive Surgery Phase 2 Withdrawn - United States, Ohio ... More >> Nationwide Children's Hospital Columbus, Ohio, United States, 43205 Less <<
NCT00638729 Anxiety Pain Not Applicable Completed - Germany ... More >> Department of Anaesthesiology and Intensive Care Medicine, University of Schleswig-Holstein Campus Kiel Kiel, Germany, 24105 Less <<
NCT03155646 Transversus Abdominis Plane Bl... More >>ock Less << Phase 2 Phase 3 Completed - Egypt ... More >> Assiut University Hospital Assiut, Egypt Less <<
NCT02530151 Femoracetabular Impingement ... More >> Pain, Postoperative Less << Phase 4 Completed - United States, Illinois ... More >> Northwestern Medicine, Department of Orthopaedic Surgery Chicago, Illinois, United States, 60611 Less <<
NCT00983125 Labour Phase 4 Completed - France ... More >> CHU Clermont-Ferrand Clermont-Ferrand, France, 63003 Less <<
NCT01638052 Tympanomastoid Surgery ... More >> Cochlear Implant Mastoidectomy Cholesteatoma Less << Phase 2 Completed - United States, Illinois ... More >> Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States, 60611 Less <<
NCT00580151 Pain Anxiety Not Applicable Terminated(Closed due to no re... More >>sponse from PI to IRB) Less << - United States, Texas ... More >> Shriners Hospital for Children; Shriners Burns Hospital Galveston, Texas, United States, 77550 Less <<
NCT00588354 - Terminated(Targeted enrollment... More >> was not reached.) Less << - -
NCT03092011 Neonatal Abstinence Syndrome Phase 4 Recruiting December 2023 United States, New Jersey ... More >> Cooper University Hospital Recruiting Camden, New Jersey, United States, 08103 Contact: Alla Kushnir, MD    856-342-2265    kushnir-alla@cooperhealth.edu Less <<
NCT00130091 Hernia, Inguinal ... More >> Hydrocele Less << Phase 2 Completed - Canada, Ontario ... More >> Children's Hospital of Eastern Ontario Ottawa, Ontario, Canada, K1H 8L1 Less <<
NCT00350532 Pain Phase 2 Completed - United States, North Carolina ... More >> The Center for Clinical Research, 145 Kimel Park Drive Winston-Salem, North Carolina, United States, 27103 Wake Forest University School of Medicine, Medical Center Boulevard Winston-Salem, North Carolina, United States, 27157-1009 Less <<
NCT00580151 - Terminated(Closed due to no re... More >>sponse from PI to IRB) Less << - -
NCT01902108 Post-operative Pain Phase 4 Completed - Lebanon ... More >> Hotel Dieu de france Hospital Beirut, Lebanon, 16-6830 Less <<
NCT02812368 Autism Spectrum Disorder Phase 2 Withdrawn(Failure to recruit) - United States, Ohio ... More >> Ohio State University Nisonger Center Columbus, Ohio, United States, 43210 Less <<
NCT01136278 Mood Disorder ... More >> Substance-Related Disorders Amphetamine-Related Disorders Less << Phase 1 Completed - Switzerland ... More >> Clinical Pharmacology & Toxicology, University Hospital Basel Basel, Switzerland, 4053 Less <<
NCT01956604 Delirium Phase 2 Terminated(The inclusion rate ... More >>was too low, due to the exclusion criteria.) Less << - Norway ... More >> Oslo University Hospital Oslo, Norway, N-0424 Less <<
NCT02324413 Negative Behaviour Change Phase 3 Completed - United Kingdom ... More >> Bristol Dental Hospital Bristol, United Kingdom, BS2 8BJ Less <<
NCT02361476 Psychomotor Agitation Phase 4 Completed - Denmark ... More >> The Juliane Marie Centre, Copenhagen University Hospital, Rigshospitalet Copenhagen, Zealand, Denmark, 2100 Køge Sygehus, Anæstesiologisk Afdeling Køge, Denmark, 4600 Anæstesiologisk afdeling, Vejle Sygehus Vejle, Denmark, 7100 Less <<
NCT00350532 - Completed - -
NCT01677351 Pain Arrythmi... More >>a Less << Phase 2 Unknown December 2012 Brazil ... More >> Federal University of Sao Paulo Recruiting Sao Paulo, Brazil Contact: Ana Ellen Santiago, investigator    55 1 69 9334 4747    ellensantiago@hotmail.com    Principal Investigator: Ana Ellen Santiago, investigator Less <<
NCT01620112 Fascicular Block ... More >> Motor Activity Pain, Postoperative Latency Period Less << Phase 2 Completed - -
NCT02181543 Is an Only Child Phase 3 Completed - Brazil ... More >> Instituto de Medicina Integral Prof. Fernando Figueira (IMIP) Recife, Pernambuco, Brazil, 50.070-550 Less <<
NCT02733757 Anesthesia Phase 2 Completed - -
NCT03018171 Labor Pain Phase 4 Recruiting August 2017 Italy ... More >> San Giovanni Calibita Fatebenefratelli, Tiberine Island, Hospital Recruiting Rome, Italy, 00186 Contact: Marco Aversano, MD    +39066837258    m.aversano@me.com    Principal Investigator: Claudia Claroni, MD Less <<
NCT00335582 Heart Disease Phase 4 Unknown December 2009 Canada, Ontario ... More >> Toronto General Hospital Toronto, Ontario, Canada, M5G 2C4 Less <<
NCT01598896 Cannabis Dependence ... More >> Marijuana Dependence Less << Phase 2 Phase 3 Terminated(low enrollment due ... More >>to limited resources) Less << - United States, Massachusetts ... More >> McLean Hospital Belmont, Massachusetts, United States, 02478 Less <<
NCT01598896 - Terminated(low enrollment due ... More >>to limited resources) Less << - -
NCT03177980 - Recruiting December 31, 2019 Sweden ... More >> Skåne Uniersity Hospital Recruiting Lund, Sweden, 221 85 Contact: Elisabeth Norman, MD, PhD    +46 705594340    elisabeth.norman@med.lu.se    Principal Investigator: Elisabeth Norman, MD, PhD          Karolinska University Hospital Not yet recruiting Stockholm, Sweden, 171 76 Contact: Boubou Hallberg, MD, PhD    + 46 70 002 10 10    boubou.hallberg@ki.se    Principal Investigator: Boubou Hallberg, MD, PhD Less <<
NCT03762317 Neonatal Abstinence Syndrome Phase 4 Recruiting December 31, 2021 United States, Minnesota ... More >> Hennepin County Medical Center Recruiting Minneapolis, Minnesota, United States, 55415 Contact: kunal gupta, MBBS, MD    612-873-2677    kunalpgimer@gmail.com Less <<
NCT02444559 Healthy Phase 2 Completed - Denmark ... More >> Department of Anesthesiology Koege Hospital Koege, Denmark, 4600 Less <<
NCT00730054 Acute Pain Re... More >>spiration Sedation Less << Phase 1 Phase 2 Completed - Norway ... More >> Dep of Anesthesia and Intensive Care, Rikshospitalet-Radiumhospitalet Medical Center Oslo, Norway, 0027 Less <<
NCT00860899 Analgesia Pai... More >>n Systemic Inflammatory Stress Response Less << Phase 4 Completed - Croatia ... More >> University Hospital Dubrava Zagreb, Croatia, 10000 Less <<
NCT01619436 Glycemia During Coronary Arter... More >>y Bypass Graft Sedation During Pre-anesthetic Medication Less << Phase 4 Completed - Brazil ... More >> National institut of Cardiology Rio de Janeiro, RJ, Brazil, 3600/100 Less <<
NCT03670160 Neonatal Abstinence Syndrome Phase 2 Recruiting September 30, 2019 United States, Tennessee ... More >> University of Tennessee Medical Center Recruiting Knoxville, Tennessee, United States, 37920 Contact: Carrie A Brusseau, PharmD    865-305-6711    cbrussea@utmck.edu Less <<
NCT00691795 Labor Pain Phase 4 Withdrawn(Study was recently t... More >>erminated due to poor enrollment - never enrolled.) Less << - United States, New York ... More >> Columbia University Medical Center New York, New York, United States, 10032 Less <<
NCT00884832 - Completed - -
NCT02545530 Renal Dialysis Not Applicable Unknown May 2016 China, Beijing ... More >> Peking University People's Hospital Recruiting Beijing, Beijing, China, 100044 Contact: Li Zuo, MD    +861088324008    zuolimd@hotmail.com    Contact: Liangying Gan, MD    +861088324005    Ganl@bjmu.edu.cn Less <<
NCT03725930 Child Preschool Phase 3 Not yet recruiting December 2019 -
NCT01784250 Anxiety Phase 2 Unknown April 2013 Colombia ... More >> Cooperative University Recruiting Envigado, Antioquia, Colombia Contact: Patricia Bermudez, Dentistry       patvanss@hotmail.com    Contact: Ana K Tamara, Physician       anakarinatamarae@hotmail.com Less <<
NCT00884832 Fecal Incontinence Phase 2 Completed - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT02068027 - Completed - -
NCT02068027 Painful Diabetic Neuropathy ... More >> Diabetic Neuropathy Neuropathy Less << Phase 2 Completed - -
NCT00370838 - Completed - -
NCT00858845 - Completed - -
NCT00858845 Heart Failure Phase 4 Completed - United States, California ... More >> University of California, Los Angeles Medical Center Los Angeles, California, United States, 90095 Less <<
NCT00370838 Tic Disorders ... More >> Tourette Syndrome Less << Phase 4 Completed - United States, Maryland ... More >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 Less <<
NCT00510016 Neonatal Abstinence Syndrome Phase 2 Completed - United States, Maryland ... More >> Johns Hopkins Medical Institutions Baltimore, Maryland, United States, 21287-3200 Less <<
NCT01846221 - Completed - -
NCT02505204 Ventral Hernia Repair Not Applicable Recruiting February 2019 Lebanon ... More >> Makassed General Hospital Recruiting Beirut, Lebanon Contact: Zoher Naja, MD    +9611636000 ext 6405    zouhnaja@yahoo.com Less <<
NCT01139996 - Terminated(Difficulty in enrol... More >>ling participants) Less << - -
NCT03552068 Parkinson's Disease ... More >> Mpulse Control Disorders Less << Phase 2 Not yet recruiting September 1, 2021 -
NCT01846221 Labor Pain Phase 4 Completed - United States, New York ... More >> Columbia University Medical Center New York, New York, United States, 10032 Less <<
NCT01360450 - Terminated(The study was tremi... More >>nated because of low accural) Less << - -
NCT01360450 Neonatal Abstinence Syndrome Phase 2 Phase 3 Terminated(The study was tremi... More >>nated because of low accural) Less << - United States, Maryland ... More >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 Less <<
NCT01139996 Delirium Phase 4 Terminated(Difficulty in enrol... More >>ling participants) Less << - United States, Georgia ... More >> Memorial Health University Medical Center Savannah, Georgia, United States, 31404 Less <<
NCT02355158 - Completed - -
NCT02355158 Painful Diabetic Neuropathy ... More >> Diabetes Less << Phase 2 Completed - United States, Arizona ... More >> Phoenix, Arizona, United States, 85023 United States, California Santa Monica, California, United States, 90404 Walnut Creek, California, United States, 94598 United States, Connecticut Waterbury, Connecticut, United States, 06708 United States, Florida Bradenton, Florida, United States, 34205 Brandon, Florida, United States, 33511 Jupiter, Florida, United States, 33458 Miami, Florida, United States, 33143 Tampa, Florida, United States, 33606 West Palm Beach, Florida, United States, 33401 United States, Georgia Columbus, Georgia, United States, 31904 United States, Kansas Kansas City, Kansas, United States, 66160 United States, Missouri Hazelwood, Missouri, United States, 63042 United States, North Carolina Winston-Salem, North Carolina, United States, 27103 United States, Rhode Island Warwick, Rhode Island, United States, 02886 United States, Texas Dallas, Texas, United States, 75230 Houston, Texas, United States, 77030 Houston, Texas, United States, 77074 San Antonio, Texas, United States, 78229 United States, Washington Renton, Washington, United States, 98507 Less <<
NCT02592915 Intraoperative Neurophysiologi... More >>cal Monitoring Pain Management Less << Phase 3 Recruiting January 2021 Belgium ... More >> Queen Fabiola Children's University Hospital Recruiting Brussels, Belgium, 1020 Contact: Bernard Wenderickx, Mr    0032 2 477 36 54    bernard.wenderickx@huderf.be    Contact: Paul Mourlhou, Mr    0032 2 477 38 85    paul.mourlhou@huderf.be    Principal Investigator: Francoise De Pooter, MD          Sub-Investigator: Philippe Van der Linden, PhD          Sub-Investigator: Paul Deltenre, PhD Less <<
NCT01986751 Pain Phase 1 Phase 2 Terminated(failure to enroll) - United States, Alabama ... More >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35233 Less <<
NCT01530373 Hot Flashes B... More >>reast Cancer Less << Phase 2 Recruiting September 2021 United States, Arkansas ... More >> Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences Recruiting Little Rock, Arkansas, United States, 722205 Contact: Allen C Sherman, PhD    501-686-8700    shermanallenc@uams.edu    Sub-Investigator: Issam Makhoul, MD          Sub-Investigator: Laura Hutchins, MD          Sub-Investigator: Rhonda Henry-Tillman, MD Less <<
NCT01761916 Preeclampsia Phase 4 Completed - Brazil ... More >> IMIP Recife, Pernambuco, Brazil, 50070-550 Less <<
NCT02096744 Healthy Phase 1 Completed - United States, Texas ... More >> 253.2486.1 Boehringer Ingelheim Investigational Site Austin, Texas, United States Less <<
NCT02439281 Postoperative Pain Not Applicable Completed - United States, Pennsylvania ... More >> Children's Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania, United States, 15201 Less <<
NCT02550444 Pregnancy Not Applicable Completed - -
NCT03477994 Delirium on Emergence Not Applicable Recruiting February 1, 2019 Egypt ... More >> Ain Shams university Recruiting Cairo, Egypt, 11566 Contact: Ayman Shoeb    01223111124    ayman.shoeb@gmail.com Less <<
NCT03121261 Inguinal Hernia ... More >> Spinal Anesthesia Less << Phase 4 Active, not recruiting July 2019 Croatia ... More >> Clinical Hospital Dubrava Zagreb, Croatia, 10000 Less <<
NCT01986751 - Terminated(failure to enroll) - -
NCT02466373 Delirium Crit... More >>ical Illness Less << Phase 3 Completed - Netherlands ... More >> Deventer Hospital Deventer, Netherlands Less <<
NCT01559012 - Completed - -
NCT02096744 - Completed - -
NCT03065933 - Terminated - -
NCT03065933 Bipolar Disorder, Mania Phase 4 Terminated - -
NCT01559012 Hyperemesis Gravidarum Phase 3 Completed - Italy ... More >> Ospedale Sant'Anna. Dipartimento di Ostetricia e Neonatologia. Servizio di Medicina Interna Torino, Italy, 10126 Less <<
NCT02769390 Postoperative Pain Phase 2 Completed - -
NCT01862250 - Completed - -
NCT02252848 Hypoxic Ischemic Encephalopath... More >>y (HIE) Less << Phase 1 Recruiting August 2019 United States, Maryland ... More >> Johns Hopkins Hospital Recruiting Baltimore, Maryland, United States, 21287 Contact: Estelle B Gauda, MD    410-614-0151    egauda@jhmi.edu    Contact: Tarrah N Ezell    410-614-0151    Tezell1@jhmi.edu    Principal Investigator: Estelle B Gauda, MD Less <<
NCT01439126 - Completed - -
NCT01439126 Attention Deficit Hyperactivit... More >>y Disorder Less << Phase 4 Completed - -
NCT01862250 Encephalopathy, Hypoxic-Ischem... More >>ic Less << Phase 1 Phase 2 Completed - United States, Maryland ... More >> Johns Hopkins Hospital Baltimore, Maryland, United States, 21287 Less <<
NCT02548806 Healthy Phase 1 Completed - United Kingdom ... More >> Simbec Research Limited Merthyr Tydfil, United Kingdom, CF48 4DR Less <<
NCT02643251 Painful Diabetic Neuropathy ... More >> Diabetic Neuropathy Neuropathy Less << Phase 2 Completed - United States, Arizona ... More >> Glendale, Arizona, United States, 85308 Phoenix, Arizona, United States, 85018 Phoenix, Arizona, United States, 85023 United States, California Anaheim, California, United States, 92801 Norco, California, United States, 92860 Sacramento, California, United States, 95821 Santa Monica, California, United States, 90404 Tustin, California, United States, 92780 United States, Florida Fort Myers, Florida, United States, 33912 Ocala, Florida, United States, 34471 Orlando, Florida, United States, 32801 Tampa, Florida, United States, 33634 West Palm Beach, Florida, United States, 33401 United States, Idaho Blackfoot, Idaho, United States, 83321 Boise, Idaho, United States, 83642 United States, Illinois Belleville, Illinois, United States, 62220 Blue Island, Illinois, United States, 60406 Chicago, Illinois, United States, 60616 United States, Missouri Hazelwood, Missouri, United States, 63042 United States, Ohio Cleveland, Ohio, United States, 44122 United States, South Carolina Spartanburg, South Carolina, United States, 29303 United States, Tennessee Knoxville, Tennessee, United States, 37909 United States, Texas Houston, Texas, United States, 77030 San Antonio, Texas, United States, 78218 San Antonio, Texas, United States, 78228 Less <<
NCT01876355 Delirium Phase 3 Not yet recruiting December 2020 Netherlands ... More >> Deventer Hospital Not yet recruiting Deventer, Overijssel, Netherlands, 7416 SE Contact: M. Zeeman       M.Zeeman@dz.nl    Contact: H.L.A. van den Oever       OevervdH@dz.nl    Sub-Investigator: M. Zeeman          Principal Investigator: H.L.A. van den Oever          Sub-Investigator: M Arbouw Less <<
NCT01297335 Hypertension Phase 2 Completed - -
NCT01297335 - Completed - -
NCT02643251 - Completed - -
NCT00142909 Opioid-Related Disorders Phase 2 Completed - United States, Connecticut ... More >> Yale University, Psychiatry New Haven, Connecticut, United States, 06519 Less <<
NCT00142909 - Completed - -
NCT00235729 Opiate Addiction Phase 3 Completed - United States, California ... More >> CNS, Cerritos Cerritos, California, United States, 90703 United States, District of Columbia CNS Psychiatric Institute of Washington Washington, District of Columbia, United States, 20016 United States, Georgia Atlanta Center for Medical Research Atlanta, Georgia, United States, 30308 United States, Illinois Alexian Center for Psychiatric Research Hoffman Estates, Illinois, United States, 60194 United States, Kentucky University of Kentucky Lexington, Kentucky, United States, 40502 United States, Maryland VA Maryland Health Care System, Baltimore Baltimore, Maryland, United States, 21201 United States, Michigan Wayne State University School of Medicine Detroit, Michigan, United States, 48207 United States, New York Richmond Medical Center Staten Island, New York, United States, 10304 United States, Pennsylvania VA Medical Center, Philadelphia Philadelphia, Pennsylvania, United States, 19104 United States, Rhode Island VA Medical Center, Providence Providence, Rhode Island, United States, 02908 United States, Tennessee Psychiatric Hospital at Vanderbilt Nashville, Tennessee, United States, 37232-8650 United States, Texas Research Across America Dallas, Texas, United States, 75234 University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229-3900 United States, Utah VA Salt Lake City Health Care System, Salt Lake City Salt Lake City, Utah, United States, 84148 United States, Washington VA Puget Sound Health Care System, Seattle Seattle, Washington, United States, 98108 United States, Wisconsin Aurora Psychiatric Hospital Wauwatosa, Wisconsin, United States, 53213 Less <<
NCT00032942 Opioid-Related Disorders Phase 3 Completed - United States, California ... More >> UCLA Medical Center Los Angeles, California, United States, 90095 United States, New York Columbia University New York, New York, United States, 10023 United States, Pennsylvania Philadelphia Veterans Medical Center Philadelphia, Pennsylvania, United States, 19104 Less <<
NCT01148992 Cocaine Related Disorders Phase 1 Terminated - United States, California ... More >> California Pacific Medical Center Research Institute San Francisco, California, United States, 94110 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 Less <<
NCT00373503 Marijuana Dependence Phase 2 Completed - United States, New York ... More >> New York State Psychiatric Institute New York, New York, United States, 10032 Less <<
NCT01844674 Malignant Melanoma, Neoplasms Phase 1 Completed - United States, California ... More >> Diablo Valley Oncology and Hematology Pleasant Hill, California, United States, 94523 United States, Michigan Karmanos Cancer Center Detroit, Michigan, United States, 48201 United States, North Carolina Duke University Health Systems Durham, North Carolina, United States, 27710 Brazil Instituto Nacional do Cancer - INCA Rio de Janeiro, RJ, Brazil, 20560-120 Hospital de Caridade de Ijui; Oncologia Ijui, RS, Brazil, 98700-000 CITO - Centro Integrado de Terapia Onco-Hematológica - Hospital da Cidade de Passo Fundo Passo Fundo, RS, Brazil, 99010-260 Hospital Sao Lucas - PUCRS Porto Alegre, RS, Brazil, 90610-000 Canada, Quebec CSSS champlain - Charles-Le Moyne Greenfield Park, Quebec, Canada, J4V 2H1 Cyprus Bank of Cyprus Oncology Center Nicosia, Cyprus, 2006 Korea, Republic of Severance Hospital, Yonsei University Health System Seoul, Korea, Republic of, 03722 Samsung Medical Center Seoul, Korea, Republic of, 06351 Asan Medical Center. Seoul, Korea, Republic of, 138-736 Less <<
NCT01020019 Cannabis Dependence ... More >> Marijuana Dependence Less << Phase 2 Phase 3 Completed - United States, New York ... More >> New York State Psychiatric Institute New York, New York, United States, 10032 Less <<
NCT02681198 Healthy Phase 1 Completed - United States, Texas ... More >> Worldwide Clinical Trials San Antonio, Texas, United States, 78217 Less <<
NCT02508805 Vertebrogenic Radiculopathy L5... More >>, S1 Less << Phase 3 Completed - Russian Federation ... More >> State Autonomous Institution Republican Clinical Centre of Neurology Kazan, Republic of Tatarstan, Russian Federation, 420021 Less <<
NCT01820442 Opioid Dependence ... More >> Buprenorphine Withdrawal Syndrome Less << Phase 1 Completed - United States, Utah ... More >> Lifetree Clinical Research Salt Lake City, Utah, United States, 84106 Less <<
NCT02801357 Substance Withdrawal Syndrome ... More >> Opiate Addiction Opiate Dependence Less << Phase 1 Completed - United States, Kansas ... More >> Overland Park, Kansas, United States, 66212 Less <<
NCT02446002 Healthy Phase 1 Completed - United States, Texas ... More >> Worldwide Clinical Trials San Antonio, Texas, United States, 78217 Less <<
NCT01675648 Opiate Dependent Patients Who ... More >>Are Undergoing Inpatient Detoxification in Singapore Less << Phase 4 Completed - Singapore ... More >> National Addictions Management Service, Institute of Mental Health, Singapore Singapore, Singapore, 539747 Less <<
NCT02725359 Thyroidectomy Phase 4 Completed - Turkey ... More >> Ataturk University Yakutiye, Erzurum, Turkey, 25100 Less <<
NCT01650649 Opioid Dependence ... More >> Methadone Withdrawal Syndrome Less << Phase 1 Completed - United States, Utah ... More >> Lifetree Clinical Research Salt Lake City, Utah, United States, 84106 Less <<
NCT01863186 Opioid Dependence ... More >> Acute Opioid Withdrawal Syndrome Less << Phase 3 Completed - United States, California ... More >> Clovis, California, United States, 93611 Escondido, California, United States, 92025 San Diego, California, United States United States, Florida Miami, Florida, United States, 33136 Orlando, Florida, United States, 32806 United States, Georgia Atlanta, Georgia, United States, 30308 United States, Illinois Oak Park, Illinois, United States, 60301 United States, Louisiana Lake Charles, Louisiana, United States, 70629 United States, Maryland Baltimore, Maryland, United States, 21229 United States, Mississippi Flowood, Mississippi, United States United States, Missouri Saint Louis, Missouri, United States United States, Ohio Dayton, Ohio, United States Mason, Ohio, United States, 45050 United States, Texas Austin, Texas, United States, 78731 Dallas, Texas, United States, 75208 DeSoto, Texas, United States, 75115 United States, Utah Orem, Utah, United States, 84058 Salt Lake City, Utah, United States, 84106 Less <<
NCT01310296 Normal Healthy Volunteers Will... More >> be Treated With Lofexidine to Understand the Absolute Bioavailability and Mass Balance Recovery of the Product Less << Phase 1 Completed - United States, Texas ... More >> Worldwide Clinical Trials San Antonio, Texas, United States, 78217 Less <<
NCT02497066 Pain Phase 3 Enrolling by invitation January 2019 -
NCT01558934 Opioid Dependence ... More >> Methadone Withdrawal Syndrome Less << Phase 1 Completed - United States, Utah ... More >> Lifetree Clinical Research Salt Lake City, Utah, United States, 84106 Less <<
NCT00661895 Hypertension Phase 4 Completed - United States, Nebraska ... More >> Creighton Community Health Center Omaha, Nebraska, United States, 68104 Less <<
NCT01020019 - Completed - -
NCT00661895 - Completed - -
NCT03161717 Epidural Analgesia Not Applicable Recruiting March 2019 Korea, Republic of ... More >> Korea University Guro Hospital Recruiting Seoul, Korea, Republic of, 08308 Contact: Seung-hoe Song, MBE    82-2-2626-1635    ssessong@korea.ac.kr    Contact: Da-in Lee    82-2-2626-2279    0124dain@gmail.com    Principal Investigator: Sang Sik Choi, MD, PhD          Sub-Investigator: Chung Hun Lee, MD          Sub-Investigator: Mi Kyoung Lee, MD, PhD Less <<
NCT00226096 CVA (Cerebrovascular Accident)... More >> Cerebral Hemorrhage Intracranial Hemorrhages Less << Not Applicable Completed - Australia, New South Wales ... More >> Concord Hospital Concord, New South Wales, Australia, 2138 Gosford Hospital Gosford, New South Wales, Australia, 2250 St George Hospital Kogarah, New South Wales, Australia, 2217 John Hunter Hospital Newcastle, New South Wales, Australia, 2310 St Vincent's Hospital Sydney, New South Wales, Australia, 2010 Royal Prince Alfred Hospital Sydney, New South Wales, Australia, 2050 Westmead Hospital Westmead, New South Wales, Australia, 2145 Australia, South Australia Royal Adelaide Hospital Adelaide, South Australia, Australia, 5000 Australia, Victoria Royal Melbourne Hospital Melbourne, Victoria, Australia, 3050 St Vincent's Hospital Melbourne, Victoria, Australia, 3065 Box Hill Hospital Melbourne, Victoria, Australia, 3128 Alfred Hospital Melbourne, Victoria, Australia, 3181 Austin Health Melbourne, Victoria, Australia Monash Medical Centre Melbourne, Victoria, Australia Australia, Western Australia Sir Charles Gairdner Hospital Perth, Western Australia, Australia, 6009 China Regional Coordinating Centre: Peking University First Hospital Beijing, China, 100034 Hospitals in China, c/o The George Institute China Beijing, China Regional Coordinating Centre: Centre for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Shanghai Institute of Hypertension, Shanghai Second Medical University Shanghai, China, 200025 New Zealand North Shore Hospital Auckland, New Zealand Christchurch Hospital Christchurch, New Zealand Less <<
NCT00000345 Opioid-Related Disorders Phase 1 Completed - United States, California ... More >> Friends Research Institute Los Angeles, California, United States, 90025 Less <<
NCT00579085 Complex Regional Pain Syndrome Phase 2 Completed - United States, Pennsylvania ... More >> Drexel University College of Medicine Department of Neurology Philadelphia, Pennsylvania, United States, 19107 Less <<
NCT00000354 Opioid-Related Disorders ... More >> Substance-Related Disorders Less << Phase 1 Completed - United States, Pennsylvania ... More >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 6178 Less <<
NCT00000358 Opioid-Related Disorders ... More >> Substance-Related Disorders Less << Phase 1 Completed - United States, Pennsylvania ... More >> University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 6178 Less <<
NCT00358293 Muscle Spasticity Phase 1 Phase 2 Completed - Israel ... More >> Tel Aviv Sourasky Medical Center- Neurology Department Tel Aviv, Israel Less <<
NCT00464958 Spasticity Mu... More >>ltiple Sclerosis Less << Phase 1 Phase 2 Terminated(Study was stopped a... More >>s the sponsor is no longer funding this project) Less << - Israel ... More >> Tel Aviv Sourasky Medical Center Tel Aviv, Israel, 64239 Less <<
NCT02016443 Unilateral Inguinal Hernia Phase 4 Completed - Turkey ... More >> Diskapi Yildirim Beyazit training and research hospital Ankara, Turkey Less <<
NCT03443466 Epidural Anesthesia Not Applicable Recruiting March 2019 Korea, Republic of ... More >> Korea University Guro Hospital Recruiting Seoul, Korea, Republic of, 08308 Contact: Seung-hoe Song, MBE    82-2-2626-1635    ssessong@korea.ac.kr    Contact: Ji-young Lee    82-2-2626-2279    ljy@kumc.or.kr    Principal Investigator: Sang Sik Choi, MD, Ph.D.          Sub-Investigator: Mi Kyung Lee, MD, Ph.D.          Sub-Investigator: Chung Hun Lee, MD          Sub-Investigator: Jung Eun Kim, MD          Sub-Investigator: Sang Hun Park, MD Less <<
NCT01437306 Healthy Phase 1 Completed - United States, Texas ... More >> Worldwide Clinical Trials San Antonio, Texas, United States, 78217 Less <<
NCT02313103 Renally Impaired Subjects Phase 1 Completed - United States, Florida ... More >> Orlando, Florida, United States Less <<
NCT01206283 Brain Injuries ... More >> Subarachnoid Hemorrhage Less << Not Applicable Completed - Bosnia and Herzegovina ... More >> Department of Neurosurgery, Clinical Centre University of Sarajevo Sarajevo, Bosnia and Herzegovina, 71000 Less <<
NCT02934061 Low Back Pain Phase 3 Completed - Romania ... More >> Opera Contract Research Organization SRL Timisoara, Timis, Romania, 300209 Less <<
NCT00287157 Traumatic Brain Injury Phase 1 Completed - Israel ... More >> Alyn Hospital Pediatric and Adolescent Rehabilitation Center Jerusalem, Israel, 01090 Less <<
NCT01782872 - Completed - -
NCT03718065 Opioid-use Disorder ... More >> Opiate Dependence Less << Phase 2 Not yet recruiting January 1, 2024 -
NCT01405950 Spasticity Due to Cerebral Pal... More >>sy Less << Phase 1 Terminated(Please see 'Further... More >> study details as provided by Acorda Therapeutics' for explanation of why study stopped.) Less << - United States, Kentucky ... More >> University of Louisville Department of Neurology dba Kentucky Neuroscience Research Health Care Outpatient Center (HCOC) Louisville, Kentucky, United States, 40202 Less <<
NCT03299998 - Completed - France ... More >> Hospices Civils de Lyon Lyon, France, 69004 Less <<
NCT01629446 Normal Healthy Volunteers Phase 1 Completed - United States, Texas ... More >> Worldwide Clinical Trials San Antonio, Texas, United States, 78217 Less <<
NCT01065987 Healthy Phase 1 Completed - Canada ... More >> Anapharm Inc. Sainte-Foy (Quebec), Canada Less <<
NCT01405950 - Terminated(Please see 'Further... More >> study details as provided by Acorda Therapeutics' for explanation of why study stopped.) Less << - -
NCT02318836 Liver Failure Phase 1 Completed - United States, Florida ... More >> Orlando Clinical Research Center Orlando, Florida, United States, 32809 Less <<
NCT01146028 Healthy Phase 1 Completed - Canada ... More >> Anapharm Inc. Sainte-Foy (Quebec), Canada Less <<
NCT02363998 Opioid Withdrawal Phase 3 Completed - United States, Arkansas ... More >> Little Rock, Arkansas, United States, 72211 Springdale, Arkansas, United States, 72764 United States, California San Diego, California, United States, 92103 United States, Florida Fort Lauderdale, Florida, United States, 33308 Hollywood, Florida, United States, 33021 Orlando, Florida, United States, 32801 United States, Georgia Atlanta, Georgia, United States, 30331 United States, Illinois Winfield, Illinois, United States, 60190 United States, Louisiana Lake Charles, Louisiana, United States, 70629 United States, Maryland Rockville, Maryland, United States, 20853 United States, Mississippi Flowood, Mississippi, United States, 39232 United States, Missouri Saint Louis, Missouri, United States, 63141 United States, New York New York, New York, United States, 10019 United States, Ohio Dayton, Ohio, United States, 45417 United States, Oregon Portland, Oregon, United States, 97214 United States, Pennsylvania Pittsburgh, Pennsylvania, United States, 15213 United States, South Carolina North Charleston, South Carolina, United States, 29405 United States, Utah Orem, Utah, United States, 84058 Less <<
NCT02882035 Anesthesia Phase 4 Completed - Belgium ... More >> Institut Jules Bordet Brussels, Belgium, 1000 Less <<
NCT00047580 Multiple Sclerosis ... More >> Muscle Spasticity Spinal Cord Injury Stroke Less << Phase 3 Completed - United States, Arizona ... More >> Radiant Research Tucson, Arizona, United States, 85710 United States, California The Neurology Center Encinitas, California, United States, 92024 Northridge Neurological Center Northridge, California, United States, 91325 The Neurology Center Oceanside, California, United States, 92056 Neurology Medical Group of Diablo Valley Walnut Creek, California, United States, 94598 United States, Colorado Colorado Neurology Movement Disorders Center Englewood, Colorado, United States, 80110 United States, Connecticut Yale Center for MS Treatment and Research New Haven, Connecticut, United States, 06510 United States, Florida Neurology Clinic Research Institution Plantation, Florida, United States, 33324 Axiom Clinical Research Tampa, Florida, United States, 33609 United States, Georgia Comprehensive Neurology Specialists, PC Atlanta, Georgia, United States, 30338 Neurotrials Research, Inc. Atlanta, Georgia, United States, 30342 United States, Illinois Springfield Clinic Neuroscience Institute Springfield, Illinois, United States, 62702 United States, Minnesota The Minneapolis Clinic of Neurology, Ltd. Minneapolis, Minnesota, United States, 55422 United States, Oklahoma Neurological Associates of Tulsa, Inc. Tulsa, Oklahoma, United States, 74136-8327 United States, Oregon Medford Neurological and Spine Clinic Medford, Oregon, United States, 97504-8456 United States, Rhode Island Sargent Rehabilitation Center Warwick, Rhode Island, United States, 02818 Less <<
NCT01782872 Total Shoulder Arthroplasty Phase 4 Completed - United States, New York ... More >> Hospital for Special Surgery New York, New York, United States, 10021 Less <<
NCT00748059 Autonomic Nervous System Disea... More >>ses Orthostatic Hypotension Dopamine Beta-Hydroxylase Deficiency Orthostatic Intolerance Less << Phase 1 Active, not recruiting December 2018 United States, Tennessee ... More >> Vanderbilt University Nashville, Tennessee, United States, 37232 Less <<
NCT03262623 Pain, Elbow Not Applicable Recruiting January 31, 2019 Lebanon ... More >> Makassed General Hospital Recruiting Beirut, Lebanon Contact: Zoher Naja, MD    +9611636000 ext 6941    zouhnaja@yahoo.com Less <<
NCT02521831 Inguinal Hernia Phase 3 Withdrawn - -
NCT02126332 Severe Acute Pancreatitis Phase 4 Unknown April 2017 France ... More >> CHU de Clermont-Ferrand Recruiting Clermont-Ferrand, France, 63003 Contact: Patrick LACARIN    04 73 75 11 95    placarin@chu-clermontferrand.fr    Sub-Investigator: Jean-Michel CONSTANTIN          Sub-Investigator: Léo BUHLER          Sub-Investigator: Jean-Yves LEFRANT          Sub-Investigator: Bernard CLAUD          Sub-Investigator: Russell CHABANNE          Sub-Investigator: Pierre-Marie BERTRAND          Sub-Investigator: Pierre-François LATERRE          Sub-Investigator: Arnaud FRIGGERI          Sub-Investigator: Samir JABER Less <<
NCT03663426 Hip Arthropathy Not Applicable Not yet recruiting December 2020 -
NCT02355678 Postoperative Nausea and Vomit... More >>ing Less << Not Applicable Completed - Lebanon ... More >> Makassed General Hospital Beirut, Lebanon Less <<
NCT01700517 PAIN Not Applicable Completed - Brazil ... More >> Hospital Madre Teresa Belo Horizonte, Minas Gerais, Brazil Less <<
NCT01700517 - Completed - -
NCT00535925 Diabetic Nephropathy Phase 4 Unknown September 2012 Italy ... More >> Department of Clinical and Experimental Medicine, Second University of Naples Naples, Italy, I-80131 Less <<
NCT01422616 Ischemic Stroke ... More >> High Blood Pressure Less << Phase 3 Recruiting February 2019 Australia, New South Wales ... More >> Royal Prince Alfred Hospital Recruiting Sydney, New South Wales, Australia, 2050 Contact: Craig S Anderson, MD    +61 2 933 4500    canderson@georgeinstitute.org.au Less <<
NCT03696199 Ankle Fractures Phase 4 Not yet recruiting February 1, 2020 -
NCT02026687 Gynecological Cancer Phase 4 Active, not recruiting - Sweden ... More >> University Hospital Linköping, Sweden, 581 85 Less <<
NCT01688752 - Withdrawn(Funding unavailable) - -
NCT01335542 Readiness to Discharge Phase 4 Completed - United States, New York ... More >> Hospital for Special Surgery New York, New York, United States, 10021 Less <<
NCT03388814 Pain, Postoperative ... More >> Breast Cancer Opioid Use Surgery Less << Early Phase 1 Withdrawn(Lack of Funding) June 2020 -
NCT03090152 Osteoarthritis, Hip Phase 4 Recruiting December 31, 2018 United States, New York ... More >> Hospital for Special Surgery Recruiting New York, New York, United States, 10021 Principal Investigator: Kethy Jules-Elysee, MD Less <<
NCT00684489 Hypertension Not Applicable Completed - -
NCT03124680 Anesthesia Not Applicable Completed - Belgium ... More >> Erasme Hospital Brussels, Belgium, 1070 Less <<
NCT03743974 Shoulder Lesions Not Applicable Completed - -
NCT03249025 Chronic Pain Syndrome Not Applicable Not yet recruiting September 1, 2018 -
NCT02496325 Pudendal Nerve Block Not Applicable Completed - France ... More >> University hospital Lapeyronie Montpellier, France, 34295 Less <<
NCT01132794 Pain Sedation Phase 3 Completed - Hong Kong ... More >> Department of Anaesthesiology, The University of Hong Kong Hong Kong, Hong Kong Less <<
NCT00413582 Postoperative Pain Not Applicable Completed - United States, Missouri ... More >> Children's Mercy Hospital Kansas City, Missouri, United States, 64108 Less <<
NCT00413582 - Completed - -
NCT01679353 Inguinal Hernia Not Applicable Completed - Korea, Republic of ... More >> Severance hospital Seoul, Korea, Republic of, 120-752 Less <<
NCT00004847 - Recruiting - United States, Maryland ... More >> Johns Hopkins University Recruiting Baltimore, Maryland, United States, 21205 National Institutes of Health Clinical Center, 9000 Rockville Pike Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)    800-411-1222 ext TTY8664111010    prpl@cc.nih.gov Less <<
NCT01335542 - Completed - -
NCT01887184 Gastrointestinal Disease Phase 3 Completed - -
NCT00504218 - Terminated - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT01600027 Children With Fracture Femur Phase 1 Completed - Egypt ... More >> Mansoura University Hospitals Mansoura, DK, Egypt, 050 Less <<
NCT01604915 Cryptorchidism Not Applicable Completed - Korea, Republic of ... More >> Severance hospital Seoul, Korea, Republic of, 120-752 Less <<
NCT03064633 Postoperative Pain Phase 4 Completed - Egypt ... More >> Fayoum University hospital Madīnat al Fayyūm, Faiyum Governorate, Egypt, 63514 Less <<
NCT01524367 Agitation Phase 4 Completed - Korea, Republic of ... More >> Gangnam severance hospital Seoul, Korea, Republic of Less <<
NCT01657812 Gastrectomy Phase 4 Unknown July 2013 China, Anhui ... More >> The Second Affiliated Hospital of Anhui Medical University Recruiting HeFei, Anhui, China, 230601 Contact: Yun Li, doctor       yunli_001@yahoo.com.cn    Contact: Ye Zhang, doctor       zhangye_hassan@yahoo.com.cn Less <<
NCT00367874 Opiate Dependence ... More >> Drug Dependence Substance Withdrawal Syndrome Less << Phase 4 Completed - Norway ... More >> Sorlandet Hospital HF, Addiction Unit (ARA) Kristiansand, Vest-Agder, Norway, N-4604 Less <<
NCT02576782 Pain Phase 4 Completed - -
NCT01172288 - Completed - -
NCT01172288 Tourettes Syndrome ... More >> Tic Less << Phase 2 Completed - United States, Connecticut ... More >> Yale Child Study Center New Haven, Connecticut, United States, 06520 Less <<
NCT00326235 Heroin Dependence Phase 4 Completed - United States, New York ... More >> VA New York Harbor Healthcare System - Brooklyn Campus Brooklyn, New York, United States, 11209 Less <<
NCT02607163 Postoperative Acute Kidney Inj... More >>ury in Patients Undergoing Aortic Surgery Less << Phase 4 Recruiting August 2018 Korea, Republic of ... More >> Department of Anesthesiology and Pain Medicine, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine Recruiting Seoul, Korea, Republic of, 03722 Contact: Sarah Soh, MD    82-2-2228-8512    yeonchoo@yuhs.ac Less <<
NCT03118076 Free Flap Reconstruction Phase 4 Not yet recruiting July 31, 2017 China, Liaoning ... More >> School & Hospital of Stomatology, China Medical University Not yet recruiting Shenyang, Liaoning, China, 110002 Contact: Xiaofeng Bai Less <<
NCT02746575 Adrenergic Beta-Receptor Block... More >>ader Troponin Levels Cardiomyopathy, Post-surgical Less << Phase 4 Active, not recruiting October 2017 United States, Missouri ... More >> Barnes-Jewish Hospital/Washington University in St. Louis School of Medicine Saint Louis, Missouri, United States, 63110 Less <<
NCT02436265 Surgery Phase 4 Terminated(Lack of enrollment/... More >>lack of potential subjects fitting criteria) Less << - United States, Indiana ... More >> Riley Hospital for Children Indianapolis, Indiana, United States, 46202 Less <<
NCT02199587 Precocious Puberty ... More >> Growth Hormone Tests Less << Not Applicable Completed - Israel ... More >> Meir Medical Center endocrine unit Kfar Saba, Israel Less <<
NCT03167047 Hernia, Inguinal Not Applicable Recruiting August 30, 2017 United Kingdom ... More >> Medway NHS Foundation Trust Recruiting Gillingham, Kent, United Kingdom, ME7 5NY Contact: Kumarvel Veerappan, FRCA    01634 830000 ext 3722    kumarvel.verrapan@nhs.net    Contact: Robert Hughes, MA    01634 830000 ext 6782    robert.hughes@medway.nhs.uk Less <<
NCT03476772 - Not yet recruiting October 2020 -
NCT02424240 - Completed - -
NCT03372486 Upper Extremity Trauma Not Applicable Completed - Egypt ... More >> Mansoura University, Central Hospital, emergency Unit Mansourah, Dakahlia, Egypt, 050 Less <<
NCT03618693 Prostatectomy ... More >> Pain Less << Not Applicable Recruiting March 1, 2021 Switzerland ... More >> Patrick Wuethrich, Department of Anaesthesiology and Pain Therapy, University Hospital Bern Inselspital Bern Recruiting Bern, BE, Switzerland, 3010 Contact: Patrick Y Wuethrich, MD    0041316322725    patrick.wuethrich@insel.ch    Contact: Fiona C Burkhard, MD    00316323977    fiona.burkhard@insel.ch    Principal Investigator: Patrick Y Wuethrich, MD Less <<
NCT00004329 - Completed - United States, Texas ... More >> University of Texas Medical Branch Galveston, Texas, United States, 77555-0209 Less <<
NCT02442128 Anesthesia Intubation Complica... More >>tion Less << Not Applicable Completed - Saudi Arabia ... More >> King Saud University Riyadh, Saudi Arabia, 11411 Less <<
NCT00390871 Sedation Phase 2 Completed - United States, Maryland ... More >> Johns Hopkins University Baltimore, Maryland, United States, 21287 Less <<
NCT02740127 Malignant Neoplasms of Male Ge... More >>nital Organs Less << Phase 3 Recruiting June 2021 United States, Texas ... More >> University of Texas MD Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Less <<
NCT00443404 Phantom Limb Pain Phase 2 Phase 3 Completed - Greece ... More >> Patras, Greece Less <<
NCT03328299 Postoperative Pain Phase 2 Phase 3 Recruiting December 2018 Egypt ... More >> South Egypt Cancer instIitute Recruiting Assuit, Egypt, 171516 Contact: fatma ad el sherif, lecturer    088233018    fatma_anesthesia@yahoo.com Less <<
NCT00004332 - Completed - -
NCT02571283 Total Knee Arthroplasty ... More >> Pain Management Less << Phase 4 Withdrawn(PI decided to focus ... More >>on more current topics of interest.) Less << - -
NCT02282787 Peribulbar Anesthesia Phase 3 Unknown May 2015 Saudi Arabia ... More >> King Abdulaziz University Hospital at King Saud University Riyadh, Saudi Arabia, 11411 Less <<
NCT02884011 - Completed - United States, Illinois ... More >> Rush Univeristy Medical Center Chicago, Illinois, United States, 60612 Less <<
NCT03643913 Shoulder Pain ... More >> Anesthesia Less << Phase 4 Not yet recruiting July 2019 Belgium ... More >> University Hospitals Leuven Not yet recruiting Leuven, Vlaams-Brabant, Belgium, 3000 Contact: Stefaan Nijs, Prof. Dr.    016 34 46 65 ext 0032    stefaan.nijs@uzleuven.be    Sub-Investigator: Steve Coppens, Dr.          Sub-Investigator: Arne Neyrinck, Prof. Dr.          Sub-Investigator: Willem Metsemakers, Prof. Dr.          Principal Investigator: Stefaan Nijs, Prof. Dr. Less <<
NCT03180203 Ventilators, Mechanical ... More >> Intensive Care Units Postoperative Care Less << Not Applicable Completed - Netherlands ... More >> Catharina Hospital Eindhoven, Noord-Brabant, Netherlands, 5623 EJ Less <<
NCT00227253 - Recruiting December 2025 United States, Texas ... More >> University of Texas Health Science Center at San Antonio Recruiting San Antonio, Texas, United States, 78229 Contact: Jannine D Cody, Ph.D.    210-567-9220    cody@uthscsa.edu    Contact: Daniel E Hale, M.D.    210-567-5284    hale@uthscsa.edu    Principal Investigator: Jannine D. Cody, Ph.D.          Sub-Investigator: Peter T. Fox, M.D.          Principal Investigator: Daniel E. Hale, M.D.          Sub-Investigator: Brian P Perry, M.D. Less <<
NCT02851303 Neonatal Abstinence Syndrome Phase 4 Recruiting January 2018 United States, New Mexico ... More >> University of New Mexico Health Sciences Center Recruiting Albuquerque, New Mexico, United States, 87106 Contact: Mary B Sutter, MD    443-386-6352    msutter@salud.unm.edu    Contact: Nicole Yonke, MD       nyonke@salud.unm.edu Less <<
NCT01839279 Spasticity Phase 2 Completed - United States, Texas ... More >> Covance- Dallas Dallas, Texas, United States, 75247 Less <<
NCT03068897 Low Back Pain Phase 4 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less <<
NCT01677767 - Completed - India ... More >> Sir Gangaram Hospital New Delhi, Delhi, India, 110060 Ahmedabad Dialysis Centre Ahmedabad, India, 380005 Excel Center Guwahati, India, 781007 ESIS Hospital; Department of Nephrology Kolkata, India, 600054 Vertex Hospital Mumbai, India, 400083 Apollo Indraprastha Hospitals; Nephrology New Delhi, India, 110076 Aditya Birla Memorial Hospital Pune, India, 411033 Less <<
NCT00283686 Kidney, Polycystic Phase 3 Completed - United States, Colorado ... More >> University of Colorado Health Sciences Center Denver (Aurora), Colorado, United States, 800045 United States, Georgia Emory University School of Medicine Atlanta, Georgia, United States, 30322 United States, Kansas University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Massachusetts Tufts University-New England Medical Center Boston, Massachusetts, United States, 02111 Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, Ohio Cleveland Clinic Foundation Cleveland, Ohio, United States, 44195 Less <<
NCT01839279 - Completed - -
NCT01677767 - Completed - -
NCT00283686 - Completed - -
NCT00421863 Hypertension Phase 4 Completed - Italy ... More >> Ospedale N. Melli San Pietro Vernotico, Brindisi, Italy, 72027 Ospedale Civile Mellini Chiari, BS, Italy, 25032 Ospedale Civile G. Chidichimo Trebisacce, Cosenza, Italy, 87075 Istituto Neuromed Pozzilli, Isernia, Italy, 86077 Presidio Ospedaliero F. Ferrari Casarano, Lecce, Italy, 73042 Nuovo Ospedale Versilia Lido di Camaiore, Lucca, Italy, 55043 Ospedale Civile Castiglione del Lago, Perugia, Italy, 06061 Ospedale Civile Beato Giacomo Villa Città della Pieve, Perugia, Italy, 06062 Presidio Ospedaliero Città di Castello Città di Castello, Perugia, Italy, 06012 Ospedale Civile Gubbio, Perugia, Italy, 06024 Presidio Ospedaliero Todi, Perugia, Italy, 06059 Ospedale Silvestrini Perugia, PG, Italy Ospedale Civile Sacile, Pordenone, Italy, 33077 Ospedale Scillesi D'America Scilla, Reggio Calabria, Italy, 89058 Ospedale Civile Thiesi, Sassari, Italy, 07047 Presidio Ospedaliero Poggibonsi, Siena, Italy, 53034 Ospedale Civile S. Antonio Abate Erice, Trapani, Italy, 91016 Ospedale S. Antonio San Daniele del Friuli, Udine, Italy, 33038 Ospedale Generale Regionale Aosta, Italy, 11100 Azienda Ospedaliera G. Rummo Benevento, Italy, 82100 Spedali Civili Brescia, Italy, 25123 Azienda Ospedaliera G. Brotzu - S. Michele Cagliari, Italy, 09134 Ospedale S. Elia Caltanissetta, Italy, 93100 Ospedale Garibaldi-Nesima Catania, Italy, 95122 Azienda Ospedaliera Mater Domini Catanzaro, Italy, 88100 Ospedale Clinicizzato Santissima Annunziata Chieti, Italy, 66013 Istituti Ospitalieri Cremona, Italy, 26100 Dimi - Disem Genova, Italy, 16132 Ospedale Generale Provinciale Gorizia, Italy, 34170 Policlinico Universitario Federico II Napoli, Italy, 80131 Azienda Ospedaliera di Perugia Perugia, Italy, 06132 Spedali Riuniti Pistoia, Italy, 51100 Ospedale Civile Ragusa, Italy, 97100 Ospedali Riuniti G. Melacrino F. Bianchi Reggio Calabria, Italy, 89124 Ospedale San Filippo Neri Roma, Italy, 00135 CTO Roma, Italy, 00145 Ospedlae San Camillo Roma, Italy, 00149 Ospedale San Camillo Roma, Italy, 00152 Ospedale San Giovanni Roma, Italy, 00184 Policlinico Universitario Sassari, Italy, 07100 Azienda Ospedaliera Siracusa, Italy, 96100 Azienda USL 4 Terni Terni, Italy, 05100 Ospedale San Vito Torino, Italy, 10134 Casa di Cura Villa Bianca Trento, Italy, 38100 Ospedale Belcolle Viterbo, Italy, 01100 Less <<
NCT00218530 Heroin Dependence Phase 1 Completed - United States, Connecticut ... More >> Substance Abuse Treatment Unit New Haven, Connecticut, United States, 06511 Less <<
NCT00716079 - Completed - -
NCT00716079 Intracerebral Hemorrhage ... More >> Stroke Hypertension Less << Not Applicable Completed - -
NCT02957786 Smoking Cessation Phase 3 Recruiting May 2019 New Zealand ... More >> National Institute for Health Innovation, University of Auckland Recruiting Auckland, North Island, New Zealand, 1072 Contact: Natalie Walker, PhD    64 9 373 7999    n.walker@auckland.ac.nz    Contact: Chris Bullen, PhD, MBChB    64 9 373 7999    c.bullen@auckland.ac.nz    Principal Investigator: Natalie Walker, PhD          Sub-Investigator: Chris Bullen, PhD;MBChB          Sub-Investigator: Joanne Barnes, PhD          Sub-Investigator: Barry Smith, PhD          Sub-Investigator: Subhash Pokhrel, PhD          Sub-Investigator: Varsha Parag, MSc (Hons) Less <<
NCT03137732 Pain, Postoperative ... More >> Wound; Abdomen Incision Less << Not Applicable Not yet recruiting June 2018 -
NCT01142830 - Completed - Italy ... More >> Ospedale Riuniti Bergamo, Italy Policlinico Universitario Catania, Italy Meyer Hospital Firenze, Italy Ospedale pediatrico Gaslini Genova, Italy Istituto Nazionale Neurologico "Carlo Besta" Milano, Italy Azienda Ospedaliera di Padova Padova, Italy Policlinico Universitario Agostino Gemelli Rome, Italy Ospedale Infantile Regina Margherita Torino, Italy Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.75mL

0.75mL

0.38mL

18.76mL

3.75mL

1.88mL

37.52mL

7.50mL

3.75mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

References

 

Historical Records

Categories