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Chemical Structure| 6090-95-5 Chemical Structure| 6090-95-5

Structure of Conduritol B epoxide
CAS No.: 6090-95-5

Chemical Structure| 6090-95-5

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Conduritol B epoxide is an irreversible inhibitor of acid β-glucosidase (GCase) with IC50 of 1 μM.

Synonyms: D,L-1,2-Anhydro-myo-inositol; specific inhibitor of glucocerebrosidase in cultured cells; CBE

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Product Citations

Product Citations

Reetu Saini ; Reeta Rani Singhania ; Anil Kumar Patel ; Chiu-Wen Chen ; Gregorz Piechota ; Cheng-Di Dong

Abstract: Globally, the demands for sustainably sourced functional foods like prebiotic oligosaccharides have been constantly increasing. This study assessed the potential of pineapple leaves (PL) as lignocellulosic feedstock for sustainable production of and hemicellulose-derived oligosaccharides through its hydrothermal pretreatment (HT) followed by controlled enzymatic hydrolysis. PL was subjected to HT at 160, 175, and 190 °C for 20, 30, 60, and 90 min without any catalyst for xylooligosaccharide (XOS) production, whereas, the resulting solid content after HT was subjected to controlled enzymatic hydrolysis by commercial cellulase using (0.5–5 mM) for glucooligosaccharides (GOS) production. HT at 160 °C for 60 min resulted in maximum yield of XOS and GOS at 23.7 and 18.3 %, respectively, in the liquid phase. Controlled enzymatic hydrolysis of HT treated (160 °C) PL solids for 20 and 30 min yielded ∼ 174 mg cellobiose/g dry biomass within 24 h, indicating overall high production.

Keywords: Conduritol B epoxide ; Pineapple leaves ; Hydrothermal pretreatment ; Prebiotics ; Xylooligosaccharides ; Glucooligosaccharides ; Sustainable development goals no. 3

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Product Details of Conduritol B epoxide

CAS No. :6090-95-5
Formula : C6H10O5
M.W : 162.14
SMILES Code : O[C@H]1[C@@]2([H])O[C@@]2([H])[C@H](O)[C@@H](O)[C@@H]1O
Synonyms :
D,L-1,2-Anhydro-myo-inositol; specific inhibitor of glucocerebrosidase in cultured cells; CBE
MDL No. :MFCD00077326
InChI Key :ZHMWOVGZCINIHW-FTYOSCRSSA-N
Pubchem ID :119054

Safety of Conduritol B epoxide

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

6.17mL

1.23mL

0.62mL

30.84mL

6.17mL

3.08mL

61.68mL

12.34mL

6.17mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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