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Chemical Structure| 1446144-04-2 Chemical Structure| 1446144-04-2

Structure of CPI-203
CAS No.: 1446144-04-2

Chemical Structure| 1446144-04-2

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CPI 203 is a potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 with an IC50 of ~37 nM (BRD4 α-screen assay).

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Product Details of CPI-203

CAS No. :1446144-04-2
Formula : C19H18ClN5OS
M.W : 399.90
SMILES Code : O=C(N)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1
MDL No. :MFCD27997886
InChI Key :QECMENZMDBOLDR-AWEZNQCLSA-N
Pubchem ID :71291068

Safety of CPI-203

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of CPI-203

epigenetics

Isoform Comparison

Biological Activity

Target
  • BET

    BRD4, IC50:37 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.50mL

0.50mL

0.25mL

12.50mL

2.50mL

1.25mL

25.01mL

5.00mL

2.50mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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