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Chemical Structure| 1883545-60-5 Chemical Structure| 1883545-60-5

Structure of CRT0066101 2HCl
CAS No.: 1883545-60-5

Chemical Structure| 1883545-60-5

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CRT0066101 reduces BrdU incorporation, increases apoptosis, blocks neurotensin (NT)-induced PKD1/2 activation, reduces NT-induced PKD-mediated Hsp27 phosphorylation, attenuates PKD1-mediated NF-κB activation, and abrogates expression of NF-κB-dependent-dependent proliferative and pro-survival proteins.

Synonyms: CRT0066101 dihydrochloride

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Product Details of CRT0066101 2HCl

CAS No. :1883545-60-5
Formula : C18H24Cl2N6O
M.W : 411.33
SMILES Code : OC1=CC=C(C2=CN(C)N=C2)C=C1C3=NC=CC(NC[C@H](N)CC)=N3.[H]Cl.[H]Cl
Synonyms :
CRT0066101 dihydrochloride
MDL No. :MFCD30182249
InChI Key :CXYCRYGNFKDPRH-FMOMHUKBSA-N
Pubchem ID :136664697

Safety of CRT0066101 2HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • PKD

    PKD1, IC50:1 nM

    PKD2, IC50:2 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.43mL

0.49mL

0.24mL

12.16mL

2.43mL

1.22mL

24.31mL

4.86mL

2.43mL

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