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Chemical Structure| 154235-83-3 Chemical Structure| 154235-83-3

Structure of CX516
CAS No.: 154235-83-3

Chemical Structure| 154235-83-3

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Ampalex is a positive allosteric modulator of AMPAR and is researched as a treatment for Alzheimer's disease.

Synonyms: BDP 12; Ampalex.; Benzoyl-Piperidine-12

4.5 *For Research Use Only !

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Product Details of CX516

CAS No. :154235-83-3
Formula : C14H15N3O
M.W : 241.29
SMILES Code : O=C(N1CCCCC1)C2=CC=C3N=CC=NC3=C2
Synonyms :
BDP 12; Ampalex.; Benzoyl-Piperidine-12
InChI Key :ANDGGVOPIJEHOF-UHFFFAOYSA-N
Pubchem ID :148184

Safety of CX516

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00858689 Fragile X Syndrome Not Applicable Completed - Canada, Ontario ... More >> Surrey Place Centre Toronto, Ontario, Canada, M5S 2C2 Less <<
NCT00858689 - Completed - -
NCT00235352 Schizophrenia Phase 2 Phase 3 Completed - United States, Massachusetts ... More >> Freedom Trail Clinic Boston, Massachusetts, United States, 02114 Less <<
NCT00001662 Alzheimer's Disease ... More >> Dementia Less << Phase 2 Completed - United States, Maryland ... More >> National Institute of Neurological Disorders and Stroke (NINDS) Bethesda, Maryland, United States, 20892 Less <<
NCT00040443 Mild Cognitive Impairment Phase 2 Completed - United States, Arizona ... More >> Pivotal Research Centers Peoria, Arizona, United States, 85381 United States, California University of California Irvine Irvine, California, United States, 92697 University of California at Los Angeles Los Angeles, California, United States, 90095 University of California, San Diego San Diego, California, United States, 92093 United States, Connecticut Yale University School of Medicine New Haven, Connecticut, United States, 06510 United States, Florida Sun Coast Gerontology Center, University of South Florida Tampa, Florida, United States, 33617 United States, Iowa Mercy Mayo Clinic Des Moines, Iowa, United States, 50314 United States, Pennsylvania University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 Less <<
NCT00040443 - Completed - -
NCT00054730 Fragile X Syndrome ... More >> Autism Less << Phase 2 Completed - United States, California ... More >> UC Davis-MIND Institute Sacramento, California, United States, 95817 United States, Illinois RUSH-Presbyterian-St. Luke's Medical Center Chicago, Illinois, United States, 60612 Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.14mL

0.83mL

0.41mL

20.72mL

4.14mL

2.07mL

41.44mL

8.29mL

4.14mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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