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Chemical Structure| 943298-08-6 Chemical Structure| 943298-08-6
Chemical Structure| 943298-08-6

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Cy7 dyes are widely used for labeling peptides, proteins and oligos etc.

Synonyms: Sulfo-Cyanine7

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of CY7

CAS No. :943298-08-6
Formula : C35H42N2O8S2
M.W : 682.85
SMILES Code : O=S(C1=CC2=C([N+](CC)=C(/C=C/C=C/C=C/C=C3N(CCCCCC(O)=O)C4=C(C=C(S(=O)(O)=O)C=C4)C\3(C)C)C2(C)C)C=C1)([O-])=O
Synonyms :
Sulfo-Cyanine7
English Name :2-(7-(1-(5-Carboxypentyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
MDL No. :MFCD26743748

Safety of CY7

Application In Synthesis of CY7

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 943298-08-6 ]

[ 943298-08-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 943298-08-6 ]
  • [ 60-23-1 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
aq. buffer; UV-irradiation;
  • 2
  • [ 146368-08-3 ]
  • [ 1251915-09-9 ]
  • [ 943298-08-6 ]
YieldReaction ConditionsOperation in experiment
23% With pyridine at 40℃; for 1h; 3.2 The compound 9-3 (7.2 g, 17.5 mmol, 1 eq) and the compound 6b-1 (5.94 g, 17.5 mmol, 1 eq) were dissolved in 108 mL of pyridine and the resulting mixture was allowed to react at 40° C. for one hour. The reaction mixture was allowed to cool to ambient temperature, and a green solid was precipitated through addition of ethyl acetate was filtered and dried under reduced pressure. The residue was purified by RP-C18 reverse phase chromatography using 30% acetonitrile aqueous solution as an eluent to obtain a pure compound 10-3 (2.59 g, 23%). Rf=0.38 (RP-C18, acetonitrile/water 3:7 v/v). 1H NMR (400 MHz, DMSO-d6): δ 7.87 (t, 2H, J=12.8 Hz), 7.72 (m, 3H), 7.50 (d, 2H, J=11.9 Hz), 7.28 (d, 2H, J=8.24 Hz), 6.58-6.49 (m, 2H), 6.36 (d, 2H, J=13.7 Hz), 4.10-4.03 (m, 4H), 1.98 (t, 2H), 1.70-1.22 (m, 21H). LC/MS, C35H41N2O8S2-, calculated value: 681.23, measured value: 681.28. λabs (water): 748 nm, λfl (water): 786 nm.
 

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