Structure of Cysteine Protease inhibitor
CAS No.: 921625-62-9
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Cysteine protease inhibitor is an inhibitor of cysteine protease.
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CAS No. : | 921625-62-9 |
Formula : | C18H14N4O |
M.W : | 302.33 |
SMILES Code : | N#CC1=NC=CC(OC2=CC=CC(C3=CC=C(C=C3)CN)=C2)=N1 |
MDL No. : | MFCD00130887 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302 |
Precautionary Statements: | P280-P305+P351+P338 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00157508 | Type 2 Diabetes ... More >> Early Nephropathy Less << | Phase 2 | Terminated | - | Italy ... More >> Clinical Research Center for Rare Diseases Ranica, Bergamo, Italy, 24020 Less << |
NCT00166166 | Hyperlipidemia | Phase 2 | Terminated(Limited clinical st... More >>aff) Less << | - | United States, Georgia ... More >> Emory University School of Medicine Atlanta, Georgia, United States, 30322 Less << |
NCT00166166 | - | Terminated(Limited clinical st... More >>aff) Less << | - | - | |
NCT00331786 | Colorectal Cancer | Phase 1 | Completed | - | United States, New York ... More >> Stony Brook University Cancer Center Stony Brook, New York, United States, 11794-8174 Less << |
NCT00399256 | Chronic Kidney Failure | Not Applicable | Terminated | - | Germany ... More >> Robert-Bosch-Hospital Stuttgart, Germany, D-70376 Less << |
NCT00170911 | Osteoporosis | Phase 2 | Completed | - | - |
NCT02113150 | Coronary Artery Disease | Phase 4 | Completed | - | Turkey ... More >> Aslı Demir Ankara, Turkey, 06100 Turkey Yuksek Ihtisas Education and Research Hospital Ankara, Turkey, 06550 Less << |
NCT02189122 | Healthy | Not Applicable | Completed | - | United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less << |
NCT02341300 | Iron-deficiency Anemia | Not Applicable | Recruiting | November 2020 | United States, New York ... More >> New York Prebyterian Hospital Weill Cornell Recruiting New York, New York, United States, 10021 Contact: Shari Gelber, MD 212-746-3182 shg7001@med.cornell.edu Contact: Chelsea Clinton, MD 734-223-6103 cmk9008@nyp.org Sub-Investigator: Chelsea Clinton, MD Principal Investigator: Shari Gelber, MD Sub-Investigator: Melissa Yoffee, RD Less << |
NCT03738878 | Hypertension | Phase 4 | Recruiting | December 31, 2020 | United States, Tennessee ... More >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37205 Contact: Nancy J Brown, MD 615-343-8701 Contact: Dustin Mayfield, RN 615-343-8701 Less << |
NCT01256775 | Intermittent Claudication | Phase 2 | Completed | - | Italy ... More >> Ospedale di Perugia Perugia, Italy, 06126 Less << |
NCT00868855 | Coronary Artery Disease | Phase 1 | Terminated(poor enrollment) | - | United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less << |
NCT00223704 | - | Completed | - | - | |
NCT02189122 | - | Completed | - | - | |
NCT00965120 | Ischaemic Heart Diseases | Not Applicable | Completed | - | United Kingdom ... More >> University of Edinburgh, 49 Little France Crescent Edinburgh, United Kingdom, EH16 4SB Less << |
NCT00685945 | - | Completed | - | - | |
NCT00517582 | Angioneurotic Edema | Phase 1 | Terminated(This study was stop... More >>ped to allow initiation of a mult-center study) Less << | - | United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37205 Less << |
NCT00685945 | Obesity | Not Applicable | Completed | - | United States, Tennessee ... More >> Vanderbilt University Medical Center-GCRC Nashville, Tennessee, United States, 37232 Less << |
NCT03030703 | Iron-deficiency ... More >> Iron Deficiency Anemia Less << | Not Applicable | Completed | - | United States, Kansas ... More >> Physical Activity and Nutrition Research Consortium Manhattan, Kansas, United States, 66502 Less << |
NCT00223704 | Cardiopulmonary Bypass ... More >> Inflammation Fibrinolysis Surgery Less << | Phase 2 Phase 3 | Completed | - | United States, Tennessee ... More >> TN Valley Healthcare System Nashville, Tennessee, United States, 37212 Vanderbilt University Nashville, Tennessee, United States, 37232 Less << |
NCT01574248 | ACE Inhibitor-associated Angio... More >>edema Less << | Phase 4 | Terminated(DSMC recommended di... More >>scontinuation for futility and feasibility) Less << | - | United States, California ... More >> University of California, San Diego San Diego, California, United States, 92093 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37235 Less << |
NCT01413542 | Hypertension ... More >>Diabetes Type 2 Less << | Not Applicable | Completed | - | United States, Tennessee ... More >> Vanderbilt University- General Clinic Research Center Nashville, Tennessee, United States, 37232 Less << |
NCT00965393 | Ischaemic Heart Diseases | Not Applicable | Completed | - | United Kingdom ... More >> University of Edinburgh, 49 Little France Crescent Edinburgh, United Kingdom, EH16 4SB Less << |
NCT01137942 | - | Unknown | July 2010 | Slovenia ... More >> Abakus Medico Recruiting Rogaska Slatina, Slovenia Contact: Bojan Tepes, MD. PhD +386 (0) 3 819 14 11 abakus.medico@volja.net Principal Investigator: Bojan Tepes, MD, Phd Sub-Investigator: Miha Skvarc, MD Less << | |
NCT00083356 | Tooth, Impacted | Phase 2 | Completed | - | United States, Maryland ... More >> National Institute of Nursing Research (NINR) Bethesda, Maryland, United States, 20892 Less << |
NCT01574248 | - | Terminated(DSMC recommended di... More >>scontinuation for futility and feasibility) Less << | - | - | |
NCT00780377 | Heart Transplantation | Not Applicable | Withdrawn(Unable to perform st... More >>udy due to unavailable drug, then unable to partner with cath lab) Less << | - | United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less << |
NCT00780481 | - | Terminated(Lack of enrollment ... More >>due to strict inclusion/exclusion criteria. Bradykinin shortage) Less << | - | - | |
NCT00300066 | - | Completed | - | Denmark ... More >> Department of Nuclear Medicine, University Hospital Aarhus, Skejby Aarhus, Brendstrupgaardsvej 100, Denmark, 8200 Department of Clinical Physiology, University Hospital of Aarhus, Aalborg Aalborg, Hobrovej 18-22, Denmark, 9000 Less << | |
NCT00462527 | - | Completed | - | Canada, Ontario ... More >> Department of Pediatric Emergency, Children's Hospital of Eastern Ontario Ottawa, Ontario, Canada, K1H 8L1 Less << | |
NCT00467311 | - | Completed | - | Mexico ... More >> Ignacio Chávez National Institute of Cardiology Mexico City, DF, Mexico, 01480 Less << | |
NCT01413542 | - | Completed | - | - | |
NCT00780481 | Obesity | Not Applicable | Terminated(Lack of enrollment ... More >>due to strict inclusion/exclusion criteria. Bradykinin shortage) Less << | - | United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less << |
NCT00504855 | Pressure Ulcer | Not Applicable | Terminated(Staffing changes re... More >>sulted in the expiration of IRB approval (2/15/12), and recruitment halted (n=84). IRB approval is now current for retrospective analysis.) Less << | March 2014 | United States, Hawaii ... More >> Shriners Hospitals for Children - Honolulu Honolulu, Hawaii, United States, 96826 Less << |
NCT01114074 | - | Unknown | April 2017 | Netherlands ... More >> Maastricht University Maastricht, Limburg, Netherlands, 6229 ER Less << | |
NCT00704743 | Colles' Fracture | Phase 3 | Completed | - | Canada, British Columbia ... More >> Department of Emergency Medicine, St Paul's Hospital Vancouver, British Columbia, Canada, V1Y 1Z1 Less << |
NCT00823823 | Displaced Forearm Fractures | Not Applicable | Completed | - | United States, Massachusetts ... More >> Childrens Hospital Boston Boston, Massachusetts, United States, 02125 Less << |
NCT00916539 | Non-displaced Scaphoid Fractur... More >>es Less << | Not Applicable | Completed | - | United States, Massachusetts ... More >> Massachusettes General Hospital Boston, Massachusetts, United States, 02114 Less << |
NCT00823823 | - | Completed | - | - | |
NCT01221207 | Diabetic Foot Ulcers | Not Applicable | Unknown | October 2012 | United States, Arizona ... More >> University of Arizona Recruiting Tucson, Arizona, United States Contact: David Armstrong, D 520-626-1349 United States, Texas Parkland Health & Hospital Systems Not yet recruiting Dallas, Texas, United States, 75235 Contact: Lawrence Lavery, DPM 214-645-0544 LLAVE1@mednet.swmed.edu Contact: Cecilia Lara 214-645-2377 cecilia.lara@utsouthwestern.edu UT Southwestern Medical Center at Dallas Not yet recruiting Dallas, Texas, United States, 75390 Contact: Lawrence Lavery, DPM 214-645-0544 LLAVE1@mednet.swmed.edu Contact: Cecilia Lara 214-645-2377 cecilia.lara@utsouthwestern.edu Scott & White Recruiting Temple, Texas, United States Contact: Douglas Murdoch, DPM 214-771-7604 DMurdoch@swmail.sw.org Less << |
NCT00780637 | Heart Transplantation | Not Applicable | Withdrawn(Bradykinin Shortage,... More >> SCCOR expired prior to BK availability, lack of enrollment.) Less << | - | United States, Tennessee ... More >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232 Less << |
NCT01238523 | Tibial Shaft Fractures in Chil... More >>dren Less << | Not Applicable | Completed | - | United States, California ... More >> Los Angeles Orthopaedic Hospital Los Angeles, California, United States, 90007 Less << |
NCT01403766 | - | Unknown | December 2012 | United States, California ... More >> University of California, Los Angeles Not yet recruiting Los Angeles, California, United States, 90095 Contact: Eileen Tsai, M.D. 310-206-8415 etsai@mednet.ucla.edu Principal Investigator: Eileen Tsai, M.D. Sub-Investigator: John Nguyen, M.D. Less << | |
NCT00561483 | - | Completed | - | United States, Ohio ... More >> Cleveland Clinic Cleveland, Ohio, United States, 44195 Less << | |
NCT01652755 | - | Unknown | May 2013 | China, Zhejiang ... More >> Jinhua central hospital Recruiting Jinhua, Zhejiang, China, 321000 Contact: Hongying Ni, MM 86 ext 57982552629 nihongying2@163.com Principal Investigator: Hongying Ni, MM Less << | |
NCT01758835 | Lateral Malleolus Fractures | Not Applicable | Completed | - | Finland ... More >> OYS, kirurgian klinkka, Oulu Oulu, Finland, 90100 Less << |
NCT01318746 | - | Completed | - | Germany ... More >> Clinical Research Unit, Department of Nephrology and Hypertension, University of Erlangen-Nürnberg Erlangen, Germany, 91054 Less << | |
NCT02047240 | - | Completed | - | Mexico ... More >> Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán" Mexico City, DF, Mexico, 14000 Less << | |
NCT01908309 | Contrast Induced Acute Kidney ... More >>Injury Less << | Early Phase 1 | Completed | - | Italy ... More >> Misericordia Hospital, ASL 9 Grosseto, Italy, 58100 Less << |
NCT02066857 | Radius; Fracture, Lower or Dis... More >>tal End Less << | Not Applicable | Completed | - | United States, Georgia ... More >> Emory Orthopaedics and Spine Center Atlanta, Georgia, United States, 30329 Less << |
NCT02095106 | Pediatric Distal Radius Fractu... More >>res Less << | Not Applicable | Completed | - | United States, California ... More >> Orthopaedic Institute for Children Los Angeles, California, United States, 90007 Less << |
NCT02095106 | - | Completed | - | - | |
NCT02233179 | Diabetic Foot | Not Applicable | Completed | - | United States, Arizona ... More >> University Medical Center Tucson, Arizona, United States, 85724 Less << |
NCT02066857 | - | Completed | - | - | |
NCT02334033 | - | Completed | - | Turkey ... More >> Ankara University School Of Medicine, Department of Cardiology Ankara, Turkey, 06230 Less << | |
NCT02433002 | - | Active, not recruiting | December 31, 2019 | United Kingdom ... More >> Derby Hospitals NHS Foundation Trust (Royal Derby Hospital) Derby, Derbyshire, United Kingdom, DE22 3NE King's College Hospital NHS Foundation Trust London, Greater London, United Kingdom, SE5 NRS Salford Royal NHS Foundation Trust (Salford Royal Hospital) Salford, Greater Manchester, United Kingdom, M6 8HD East Kent Hospitals NHS Trust (Kent & Canterbury Hospital) Canterbury, Kent, United Kingdom, CT1 3NG University Hospitals of Leicester NHS Trust (Leicester General Hospital) Leicester, Leicestershire, United Kingdom, LE54PW University Hospital Birmingham NHS Trust (Queen Elizabeth Hospital Birmingham) Birmingham, West Midlands, United Kingdom, B15 2TH Less << | |
NCT02614690 | Fracture of Shaft of Radius an... More >>d/or Ulna Metaphyseal Fracture of Bone of Upper Limb Fracture of Upper Limb, Level Unspecified Less << | Not Applicable | Unknown | January 2017 | United States, Connecticut ... More >> Connecticut Children's Medical Center Recruiting Hartford, Connecticut, United States, 06016 Contact: Matt Solomito 860-284-0208 mailto:msolomito@ccmckids.org Principal Investigator: Mark Lee, MD Less << |
NCT00916539 | - | Completed | - | - | |
NCT02822404 | Kidney Diseases | Not Applicable | Active, not recruiting | September 2020 | France ... More >> CHU Toulouse Toulouse, France, 31059 Less << |
NCT02894164 | - | Completed | - | Sweden ... More >> Karolinska Institute Stockholm, Sweden, 171 77 Less << | |
NCT02894983 | Colles' Fracture ... More >> Distal Radius Fracture Less << | Not Applicable | Completed | - | Finland ... More >> Central Finland Central Hospital Jyväskylä, Finland Satakunta Central Hospital Pori, Finland Tampere Univeristy Hospital Tampere, Finland Less << |
NCT02276066 | Sepsis | Phase 4 | Recruiting | April 2020 | United States, Florida ... More >> UF Health at Shands hospital Recruiting Gainesville, Florida, United States, 32610 Contact: Jennifer Lanz, MSN 352-273-5497 jennifer.lanz@surgery.ufl.edu Contact: Ruth Davis, ASN 325-273-5497 ruth.davis@surgery.ufl.edu Less << |
NCT01474473 | Foot Ulcer Di... More >>abetes Mellitus Diabetic Neuropathy Less << | Not Applicable | Completed | - | France ... More >> Pitié-Salpêtrière Hospital Paris, France, 75013 Less << |
NCT03297047 | Salter-Harris Type I ... More >> Salter-Harris Type 2 Radius Fractures Forearm Fracture Less << | Not Applicable | Not yet recruiting | June 30, 2019 | - |
NCT03468023 | Radius Fracture Distal | Not Applicable | Recruiting | October 20, 2019 | Italy ... More >> Ospedale Civile Maggiore Borgo Trento Recruiting Verona, Italy, 37126 Contact: Giovanni Dib, MD +39 349 121 4908 dib.giovanni@gmail.com Contact: Matteo Cengarle, MD +39 340 981 7025 matteo_29@hotmail.com Less << |
NCT03240471 | Distal Radius Fracture | Not Applicable | Active, not recruiting | December 2019 | Netherlands ... More >> Rijnstate hospital Arnhem, Netherlands Ziekenhuis Gelderse Vallei Ede, Netherlands Radboudumc Nijmegen, Netherlands Less << |
NCT03486184 | - | Not yet recruiting | April 30, 2020 | - | |
NCT03610191 | - | Recruiting | July 1, 2020 | China, Shaanxi ... More >> Xijing Hospital Recruiting Xi'an, Shaanxi, China, 710032 Contact: Jing Zhao, M.D. 13892810471 Contact: Lihong Hou, M.D., Ph.D. +862984775337 Less << | |
NCT03170687 | Acute Closed Fracture of Proxi... More >>mal Fifth Metatarsal (Zone II) Less << | Not Applicable | Completed | - | Thailand ... More >> Jatupon Kongtharvonskul Bangkok, Select..., Thailand, 10400 Less << |
NCT03751397 | - | Not yet recruiting | December 2019 | Switzerland ... More >> University of Basel Children's Hospital Not yet recruiting Basel, Switzerland, 4031 Contact: Tatjana Welzel, Dr. med +41 (0)61 704 18 17 tatjana.welzel@ukbb.ch Less << | |
NCT00080236 | Liver Transplantation ... More >> Hepatitis Cholestasis Carcinoma, Hepatocellular Less << | Phase 2 | Completed | - | United States, Arizona ... More >> Mayo Clinic Scottsdale Phoenix, Arizona, United States, 85054 United States, California University of California Los Angeles Los Angeles, California, United States, 90095 University of California San Francisco San Francisco, California, United States, 94143 United States, Indiana Indiana University Medical Center Indianapolis, Indiana, United States, 46202 United States, Louisiana Tulane University Hospital and Clinic New Orleans, Louisiana, United States, 70112 United States, Minnesota Mayo Clinic Rochester Rochester, Minnesota, United States, 55905 United States, New York Mount Sinai School of Medicine New York City, New York, United States, 10029 United States, Ohio University of Cincinnati Cincinnati, Ohio, United States, 45267 United States, Texas Baylor Regional Transplant Institute, Baylor University Medical Center Dallas, Texas, United States, 75246 The University of Texas Health Science Center at San Antonio San Antonio, Texas, United States, 78229 Germany Oberarzt der Klinik für Allgemein-, Viszeral- und Transplantationschirurgie Charité-Virchow Berlin, Germany, D-13353 Klinik für Viszeral- und Transplantationschirurgie Medizinische Hochschule Hannover Hannover, Germany, D-30623 Abteilung für Transplantationschirurgie Johannes Gutenberg-Universität Mainz Mainz, Germany, 55101 Less << |
NCT00088140 | Hepatitis C, Chronic | Phase 2 | Completed | - | United States, Arizona ... More >> Mayo Clinic Hospital Phoenix, Arizona, United States, 85054 United States, California Scripps Clinic La Jolla, California, United States, 92067 California Pacific Medical Center San Francisco, California, United States, 94115 University of California, San Francisco San Francisco, California, United States, 94143 United States, Florida University of Miami Miami, Florida, United States, 33136 United States, Indiana Indiana University School of Medicine Indianapolis, Indiana, United States, 46202 United States, Massachusetts Beth Israel Deaconness Medical Center Boston, Massachusetts, United States, 02215 United States, Michigan Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, Minnesota The Mayo Clinic Rochester, Minnesota, United States, 55905 United States, New York Mt. Sinai School of Medicine New York City, New York, United States, 10029 United States, North Carolina University of North Carolina Chapel Hill, North Carolina, United States, 27599 Duke University Medical Center Durham, North Carolina, United States, 27715 United States, Ohio University of Cincinnati Cincinnati, Ohio, United States, 45267 Metrohealth Medical Center Cleveland, Ohio, United States, 44109 United States, Virginia Medical College of Virginia Richmond, Virginia, United States, 23298 Less << |
NCT02686762 | Non-alcoholic Steatohepatitis ... More >> Fibrosis Liver Diseases Less << | Phase 2 | Active, not recruiting | January 2019 | - |
NCT01653899 | Diabetes | Phase 1 Phase 2 | Completed | - | Canada, Alberta ... More >> University of Alberta Edmonton, Alberta, Canada Less << |
NCT03617055 | - | Not yet recruiting | July 1, 2020 | - | |
NCT02960204 | Cirrhosis Por... More >>tal Hypertension Non-alcoholic Steatohepatitis Less << | Phase 2 | Active, not recruiting | April 2019 | - |
NCT03205345 | Decompensated Cirrhosis | Phase 2 | Recruiting | August 2019 | - |
NCT02798614 | Colles' Fracture | Not Applicable | Completed | - | - |
NCT02945241 | Methicillin-resistant Staphylo... More >>coccus Aureus Sepsis Critical Illness Less << | Phase 1 | Completed | - | - |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.31mL 0.66mL 0.33mL |
16.54mL 3.31mL 1.65mL |
33.08mL 6.62mL 3.31mL |
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Dissolving Methods |
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
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