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Chemical Structure| 13095-47-1 Chemical Structure| 13095-47-1

Structure of D-α-Hydroxyglutaric acid
CAS No.: 13095-47-1

Chemical Structure| 13095-47-1

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D-α-Hydroxyglutaric acid is the main metabolic product of D-2-hydroxyglutaric aciduria, inhibiting various α-ketoglutarate-dependent dioxygenases (Ki = 10.87 mM). It also increases ROS production, inhibiting ATP synthase and the mTOR signaling pathway, making it suitable for metabolism and neurological disease research.

Synonyms: (R)-2-Hydroxyglutarate; (R)-2-Hydroxyglutaric acid; D-2-Hydroxyglutaric Acid

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Product Details of D-α-Hydroxyglutaric acid

CAS No. :13095-47-1
Formula : C5H8O5
M.W : 148.11
SMILES Code : O=C(O)[C@H](O)CCC(O)=O
Synonyms :
(R)-2-Hydroxyglutarate; (R)-2-Hydroxyglutaric acid; D-2-Hydroxyglutaric Acid
MDL No. :MFCD16251406
InChI Key :HWXBTNAVRSUOJR-GSVOUGTGSA-N
Pubchem ID :439391

Safety of D-α-Hydroxyglutaric acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of D-α-Hydroxyglutaric acid

PI3K-AKT

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

6.75mL

1.35mL

0.68mL

33.76mL

6.75mL

3.38mL

67.52mL

13.50mL

6.75mL

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