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Type HazMat fee for 500 gram (Estimated)
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Limited Quantity USD 15-60
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Chemical Structure| 10605-03-5 Chemical Structure| 10605-03-5

Structure of Dehydrocorydaline chloride
CAS No.: 10605-03-5

Chemical Structure| 10605-03-5

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Dehydrocorydaline chloride (13-Methylpalmatine chloride), an alkaloid, modulates the protein expression of Bax and Bcl-2, activates caspase-7 and caspase-8, and inactivates PARP. It also enhances p38 MAPK activation and exhibits anti-inflammatory and anti-cancer activities. Additionally, Dehydrocorydaline chloride demonstrates strong anti-malarial effects (IC50 =38 nM) and low cytotoxicity (cell viability > 90%) against the P. falciparum 3D7 strain.

Synonyms: 13-Methylpalmatine chloride; Dehydrocorydaline (chloride)

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Product Details of Dehydrocorydaline chloride

CAS No. :10605-03-5
Formula : C22H24ClNO4
M.W : 401.88
SMILES Code : CC1=C2[N+](CCC3=C2C=C(OC)C(OC)=C3)=CC4=C(OC)C(OC)=CC=C14.[Cl-]
Synonyms :
13-Methylpalmatine chloride; Dehydrocorydaline (chloride)
MDL No. :MFCD01937870

Safety of Dehydrocorydaline chloride

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H315
Precautionary Statements:P264-P270-P280-P301+P310+P330-P332+P313-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Dehydrocorydaline chloride

epigenetics
DNA
MAPK
pyroptosis
TLR

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.49mL

0.50mL

0.25mL

12.44mL

2.49mL

1.24mL

24.88mL

4.98mL

2.49mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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