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Chemical Structure| 2820126-49-4 Chemical Structure| 2820126-49-4

Structure of DHFR-IN-4
CAS No.: 2820126-49-4

Chemical Structure| 2820126-49-4

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DHFR-IN-4 is an effective dihydrofolate reductase (DHFR) inhibitor with an IC50 of 123 nM. This compound also exhibits inhibitory activity against EGFR and HER2, with IC50 values of 246 nM and 357 nM, respectively, demonstrating broad-spectrum anti-cancer activity, suitable for cancer therapy research.

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Product Details of DHFR-IN-4

CAS No. :2820126-49-4
Formula : C18H21N5O2S
M.W : 371.46
SMILES Code : O=C(C1=CSC2=NC(CN3CCOCC3)=C(C4=CC=C(C)C=C4)N21)NN
MDL No. :N/A

Safety of DHFR-IN-4

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of DHFR-IN-4

RTK
JAK-STAT

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.69mL

0.54mL

0.27mL

13.46mL

2.69mL

1.35mL

26.92mL

5.38mL

2.69mL

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