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Chemical Structure| 52328-98-0 Chemical Structure| 52328-98-0

Structure of Dimethylcurcumin
CAS No.: 52328-98-0

Chemical Structure| 52328-98-0

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Dimethylcurcumin (ASC-J9) is an androgen receptor degradation enhancer that effectively suppresses the proliferation and invasion of castration-resistant prostate cancer cells.

Synonyms: ASC-J9; GO-Y025

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Product Details of Dimethylcurcumin

CAS No. :52328-98-0
Formula : C23H24O6
M.W : 396.43
SMILES Code : O=C(/C=C(O)/C=C/C1=CC=C(OC)C(OC)=C1)/C=C/C2=CC=C(OC)C(OC)=C2
Synonyms :
ASC-J9; GO-Y025
MDL No. :MFCD12912341
InChI Key :ZMGUKFHHNQMKJI-CIOHCNBKSA-N
Pubchem ID :6477182

Safety of Dimethylcurcumin

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01289574 Acne PHASE2 COMPLETED 2025-08-12 TKL Research, Inc, Paramus, Ne... More >>w Jersey, 07652, United States|Chang Gung Memorial Hospital, NiaoSong District, Kaohsiung City, Taiwan|Shih Kong Wu Ho-Su Memorial Hospital, Taipei City, Taipei, 11160, Taiwan|Tri-Service General Hospital, Taipei City, Taipei, 11490, Taiwan|Taipei Medical University Hospital, Taipei City, Taipei, Taiwan|Chang Gung Memorial Hospital - Linkou Branch, Gueishan Township, Taoyuan County, 33305, Taiwan|Wan Fang Hospital, Taipei, 11696, Taiwan Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.52mL

0.50mL

0.25mL

12.61mL

2.52mL

1.26mL

25.23mL

5.05mL

2.52mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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