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Chemical Structure| 886-38-4 Chemical Structure| 886-38-4
Chemical Structure| 886-38-4

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Synonyms: Diphencyprone; DPC; DPCP and Diphenylcyclopropenone,

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Product Details of Diphenylcyclopropenone

CAS No. :886-38-4
Formula : C15H10O
M.W : 206.24
SMILES Code : O=C1C(C2=CC=CC=C2)=C1C3=CC=CC=C3
Synonyms :
Diphencyprone; DPC; DPCP and Diphenylcyclopropenone,
MDL No. :MFCD00001311
InChI Key :HCIBTBXNLVOFER-UHFFFAOYSA-N
Pubchem ID :65057

Safety of Diphenylcyclopropenone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H317
Precautionary Statements:P280

Application In Synthesis of Diphenylcyclopropenone

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 886-38-4 ]

[ 886-38-4 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 771-84-6 ]
  • [ 368-39-8 ]
  • [ 886-38-4 ]
  • 3-Ethoxy-3-(α-carbamoyl-α-cyanbenzyl)-1,2-diphenylcycloprop-1-en [ No CAS ]
  • 2
  • [ 52833-63-3 ]
  • [ 886-38-4 ]
  • 4'-fluoro-2'-methyl-2-phenylspiro[indene-1,1'-isoindolin]-3'-one [ No CAS ]
  • 3
  • [ 3382-18-1 ]
  • [ 886-38-4 ]
  • 8,9-dimethoxy-10b-hydroxy-2,3-diphenyl-5,6-dihydropyrrolo[2,1-a]isoquinolin-1-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
65% With air; In chloroform; at 20℃; for 3h; To a stirred solution of 6,7-dimethoxy-3,4-dihydroisoquinoline[34] (0.09 g, 0.48 mmol) in chloroform (5 mL), was added diphenylcyclopropenone(0.10 g, 0.48 mmol) at room temperature under an air atmosphere. The reaction mixture was stirred for 3 h and then the solvent was removed by rotary evaporation. The crude product was purified by flash chromatography affording the title compound as an orange yellow solid (0.13 g, 65% yield), m.p.154-156 C. Rf 0.30 (ethyl acetate/hexane, 1:1); 1H NMR (400 MHz,CDCl3) δ: 7.64 (1H, s, Ar), 7.51e7.46 (5H, m, Ar), 7.12e7.01 (3H, m,Ar), 7.00 (2H, d, J 7.5 Hz, Ar), 6.54 (1H, s, Ar), 4.00 (3H, s, OCH3), 3.86 (3H, s, OCH3), 3.89e3.81 (1H, m, CHH), 3.60 (2H, m, CHH &OH), 2.65e2.57 (1H, m, CHH), 2.47 (1H, bd, J 14.0 Hz, CHH); 13CNMR (100 MHz, CDCl3) δ : 198.1 (C]O), 173.8 (qC), 149.4 (qC), 148.5(qC), 130.69 (CH), 130.66 (qC), 130.5 (qC), 129.8 (CH), 129.2 (CH),128.8 (CH), 127.9 (CH), 126.6 (qC), 126.0 (CH), 124.9 (qC), 113.2 (qC),110.3 (CH), 110.3 (CH), 85.4 (qC), 56.2 (CH3), 55.9 (CH3), 40.7 (CH2),28.9 (CH2); IR (neat, cm1) ν max: 3250.1, 2921.1, 2852.2, 1643.7,1446.6, 1360.1, 1257.0, 1223.2, 1124.7, 1037.7; HRMS: [M] forC26H23NO4 calculated 413.1627, found 413.1617.
 

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