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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 138148-68-2 Chemical Structure| 138148-68-2

Structure of DM1-SMe
CAS No.: 138148-68-2

Chemical Structure| 138148-68-2

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DM1-SMe is a non-binding form of Maytansinoid in IMGN901. In a panel of human tumor cell lines, DM1-SMe is approximately 3-10 times more potent than the parent Maytansinoid, with IC50 values ranging from 0.003 to 0.01 nM.

4.5 *For Research Use Only !

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Product Details of DM1-SMe

CAS No. :138148-68-2
Formula : C36H50ClN3O10S2
M.W : 784.38
SMILES Code : C[C@@]1([C@@H](O1)[C@H](C)[C@]([H])(C[C@](N2)(O)[C@]([H])(OC)/C=C/C=C(C3)\C)OC2=O)[C@@]([H])(OC([C@@H](N(C(CCSSC)=O)C)C)=O)CC(N(C)C4=CC3=CC(OC)=C4Cl)=O
MDL No. :MFCD28400100

Safety of DM1-SMe

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H303-H312-H315-H319-H361-H372-H317-H351-H335-H336-H412
Precautionary Statements:P501-P273-P272-P260-P270-P202-P201-P271-P264-P280-P312-P337+P313-P305+P351+P338-P362+P364-P333+P313-P302+P352+P312-P304+P340+P312-P403+P233-P405
Class:6.1
UN#:2811
Packing Group:

Related Pathways of DM1-SMe

cytoskeleton

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.27mL

0.25mL

0.13mL

6.37mL

1.27mL

0.64mL

12.75mL

2.55mL

1.27mL

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