Structure of DMP 777
CAS No.: 157341-41-8
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
DMP 777 is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.
Synonyms: L-694458
4.5
*For Research Use Only !
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 157341-41-8 |
Formula : | C31H40N4O6 |
M.W : | 564.67 |
SMILES Code : | O=C(N1[C@@H](OC2=CC=C(C(N3CCN(C)CC3)=O)C=C2)C(CC)(CC)C1=O)N[C@@H](C4=CC=C(OCO5)C5=C4)CCC |
Synonyms : |
L-694458
|
MDL No. : | MFCD00871548 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00116493 | Anemia | Phase 3 | Completed | - | Pakistan ... More >> Aga Khan University Karachi, Sindh, Pakistan Less << |
NCT01327469 | Infection by Trichuris Trichiu... More >>ra Less << | Phase 4 | Completed | - | Ethiopia ... More >> Jimma University Jimma, Ethiopia Less << |
NCT00080444 | Vomiting | Phase 3 | Completed | - | - |
NCT03278431 | Hookworm Infection | Phase 4 | Completed | - | Lao People's Democratic Republ... More >>ic Nambak District Hospital Luang Prabang, Lao People's Democratic Republic, 0604 Less << |
NCT01050452 | Parasitic Diseases | Not Applicable | Completed | - | Uganda ... More >> Vector Control Division Kampala, Uganda Less << |
NCT01050374 | Parasitic Diseases | Not Applicable | Completed | - | Uganda ... More >> Vector Control Division Kampala, Uganda Less << |
NCT00000314 | Cocaine-Related Disorders | Phase 2 | Completed | - | United States, New York ... More >> VA Medical Center Brooklyn, New York, United States, 11209 Less << |
NCT01350271 | Necator Americanus Infection | Phase 3 | Completed | - | Sri Lanka ... More >> Agalawatta Plantations PLC Nivitigala, Sabragamuwa, Sri Lanka Lellopitiya Estate, Hapugastenne Plantations PLC Ratnapura, Sabragamuwa, Sri Lanka Less << |
NCT01350271 | - | Completed | - | - | |
NCT01379326 | Ascaris Lumbricoides ... More >> Ascaris Suum Trichuris Trichiura Trichuris Vulpis Ancylostoma Duodenal Ancylostoma Caninum Ancylostoma Ceylanicum Necator Americanus Less << | Phase 4 | Completed | - | Argentina ... More >> Fundacion Huesped Buenos Aires, Argentina Australia Commonwealth Scientific and Industrial Research Organisation Brisbane, Australia Queensland Institute for Medical Research, University of Queensland Herston QLD, Australia Brazil Fundação Oswaldo Cruz Belo Horizonte, Brazil Cambodia Institut Pasteur in Cambodia, Clinical Pathology Unit Phnom Penh, Cambodia Cameroon University of Yaoundé I Yaoundé I, Cameroon Ethiopia College of Public Health and Medical Sciences, Jimma University Jimma, Ethiopia Tanzania Ivo de Carneri, Pemba Island Zanzibar, Tanzania Vietnam National Institute for Malariology, Parasitology and Entomology Hanoi, Vietnam Less << |
NCT03472573 | Recurrent B Acute Lymphoblasti... More >>c Leukemia Refractory B Acute Lymphoblastic Leukemia Less << | Phase 1 | Recruiting | November 2020 | United States, Pennsylvania ... More >> Sidney Kimmel Cancer Center at Thomas Jefferson University Recruiting Philadelphia, Pennsylvania, United States, 19107 Contact: Margaret Kasner, MD 215-955-8874 margaret.kasner@jefferson.edu Principal Investigator: Margaret Kasner, MD Less << |
NCT03245398 | Hookworm | Phase 4 | Completed | - | Tanzania ... More >> Public Health Laboratory Ivo de Carneri, P.O. Box 122 Chake Chake, Pemba, Tanzania Less << |
NCT01208233 | Ischemic Stroke | Phase 2 | Terminated(See termination rea... More >>son in detailed description.) Less << | - | - |
NCT03628079 | Cancer of the Gastrointestinal... More >> Tract Cancer of Unknown Origin Less << | Phase 1 Phase 2 | Recruiting | June 2020 | Sweden ... More >> Dept of oncology, University Hospital Recruiting Uppsala, Sweden, 75185 Less << |
NCT02201381 | Cancer Overal... More >>l Survival Less << | Phase 3 | Recruiting | October 22, 2023 | United Kingdom ... More >> Care Oncology Clinic Recruiting London, United Kingdom, W1G 9PP Contact: Gregory Stoloff +44 207 580 3266 info@careoncologyclinic.com Contact: Robin Bannister, PhD +44 207 153 6577 robin.bannister@seekacure.com Less << |
NCT02492334 | PTSD Alcohol ... More >>Use Disorder Less << | Phase 1 Phase 2 | Recruiting | March 2019 | United States, South Carolina ... More >> Addiction Sciences Division-Medical University of South Carolina Recruiting Charleston, South Carolina, United States, 29425 Contact: Megan M Moran-Santa Maria, Ph.D. moranm@musc.edu Contact: Francis M Beylotte, MS 8437922522 ext Beylotte beylott@musc.edu Sub-Investigator: Julianne Flanagan, Ph.D. Principal Investigator: Sudie Back, Ph.D. Less << |
NCT01837862 | Pilomyxoid Astrocytoma ... More >> Pilocytic Astrocytoma Glioma, Astrocytic Optic Nerve Glioma Pleomorphic Xanthoastrocytoma Glioblastoma Multiforme Anaplastic Astrocytoma Gliosarcoma Diffuse Intrinsic Pontine Glioma DIPG Low-grade Glioma Brainstem Glioma Less << | Phase 1 Phase 2 | Recruiting | April 2020 | United States, New York ... More >> Cohen Children's Medical Center of New York Recruiting New Hyde Park, New York, United States, 11040 Contact: Mark P Atlas, MD 718-470-3460 matlas@nshs.edu Contact: Derek R Hanson, MD 551-996-5437 DHanson@hackensackumc.org Principal Investigator: Mark P Atlas, MD Sub-Investigator: Derek R Hanson, MD Sub-Investigator: Arlene Redner, MD Sub-Investigator: Mohamad Badawi, MD Sub-Investigator: Avery Wright, DO Less << |
NCT01208233 | - | Terminated(See termination rea... More >>son in detailed description.) Less << | - | - | |
NCT01450683 | Prostate Cancer ... More >> Prostatic Neoplasms Castrate-resistant Prostate Cancer (CRPC) Androgen-insensitive Prostate Cancer Hormone-refractory Prostate Cancer Metastatic Disease Less << | Phase 2 | Terminated(Low accrual) | - | United States, California ... More >> Stanford University School of Medicine Stanford, California, United States, 94305 Less << |
NCT01173562 | Healthy Volunteers | Phase 3 | Completed | - | Tanzania ... More >> Pemba, Tanzania Less << |
NCT01161069 | Healthy | Phase 1 | Completed | - | Belgium ... More >> Pfizer Investigational Site Bruxelles, Belgium, 1070 Less << |
NCT01450683 | - | Terminated(Low accrual) | - | - | |
NCT02385058 | Helminthiasis ... More >> Amoebiasis Less << | Phase 4 | Completed | - | Mexico ... More >> Mex, Mexico Less << |
NCT02152527 | - | Completed | - | Croatia ... More >> School of Medicine, University of Split Split, Croatia, 21000 Less << | |
NCT02034162 | - | Completed | - | - | |
NCT02034162 | Helminth Infections | Phase 3 | Completed | - | Ethiopia ... More >> Gondar, Ethiopia Jimma, Ethiopia Rwanda Kigali, Rwanda Less << |
NCT01395381 | Kwashiorkor M... More >>arasmus Less << | Not Applicable | Withdrawn(not funded) | - | Malawi ... More >> St. Louis Nutrition Project Blantyre, Malawi Less << |
NCT02255461 | Childhood Choroid Plexus Tumor... More >> Childhood Ependymoblastoma Childhood Grade III Meningioma Childhood High-grade Cerebellar Astrocytoma Childhood High-grade Cerebral Astrocytoma Childhood Medulloepithelioma Recurrent Childhood Anaplastic Astrocytoma Recurrent Childhood Anaplastic Oligoastrocytoma Recurrent Childhood Anaplastic Oligodendroglioma Recurrent Childhood Brain Stem Glioma Recurrent Childhood Cerebellar Astrocytoma Recurrent Childhood Cerebral Astrocytoma Recurrent Childhood Giant Cell Glioblastoma Recurrent Childhood Glioblastoma Recurrent Childhood Gliomatosis Cerebri Recurrent Childhood Gliosarcoma Recurrent Childhood Medulloblastoma Recurrent Childhood Pineoblastoma Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor Less << | Phase 1 | Recruiting | December 31, 2018 | United States, California ... More >> Childrens Hospital Los Angeles Recruiting Los Angeles, California, United States, 90027 Contact: Girish Dhall 323-361-4629 gdhall@chla.usc.edu Principal Investigator: Girish Dhall Lucile Packard Children Hospital Stanford University Recruiting Palo Alto, California, United States, 94304 Contact: Paul G. Fisher 650-721-5889 pfisher@stanford.edu Principal Investigator: Paul G. Fisher United States, District of Columbia Childrens National Medical Center Recruiting Washington, District of Columbia, United States, 20010-2970 Contact: Eugene Hwang, MD 202-476-5046 ehwang@childrensnational.org Principal Investigator: Lindsay B Kilburn, MD Sub-Investigator: Roger Packer, MD Sub-Investigator: Brain Rood, MD Sub-Investigator: Eugene Hwang, MD United States, Illinois Lurie Childrens Hospital-Chicago Recruiting Chicago, Illinois, United States, 60614 Contact: Stewart Goldman 312-227-4874 sgoldman@luriechildrens.org Principal Investigator: Stewart Goldman, MD Sub-Investigator: Jason Fangusaro, MD Sub-Investigator: Rishi Lulla, MD Sub-Investigator: Natasha Pillay-Smiley, MD United States, New York Memorial Sloan Kettering Cancer Center Recruiting New York, New York, United States, 10065 Contact: Ira Dunkel 212-639-2153 dunkeli@mskcc.org Principal Investigator: Ira Dunkel United States, North Carolina Duke University Medical Center Recruiting Durham, North Carolina, United States, 27710 Contact: David Van Mater, MD, PhD 919-684-3401 david.vanmater@duke.edu Principal Investigator: David Van Mater United States, Ohio Cincinnati Children Hospital Medical Center Recruiting Cincinnati, Ohio, United States, 45229 Contact: Maryam Fouladi 513-803-0721 maryam.fouladi@cchmc.org Principal Investigator: Maryam Fouladi United States, Pennsylvania Children Hospital of Pittsburgh of UPMC Recruiting Pittsburgh, Pennsylvania, United States, 15224 Contact: Ian Pollack 412-692-5881 Pollaci@chp.edu Sub-Investigator: Ian Pollack, MD Principal Investigator: A. Kim Ritchey, MD United States, Tennessee St. Jude Children Research Hospital Recruiting Memphis, Tennessee, United States, 38105 Contact: Giles Robinson, MD 901-595-2907 giles.robinson@stjude.org Principal Investigator: Zsila Sadighi, MD Sub-Investigator: Amar Gajjar, MD United States, Texas Texas Childrens Hospital Recruiting Houston, Texas, United States, 77030 Contact: Patricia M. Baxter, MD 832-824-4681 pabaxter@txch.org Sub-Investigator: Murali M. Chintagumpala Principal Investigator: Patricia Baxter United States, Washington Seattle Children Hospital Recruiting Seattle, Washington, United States, 98105 Contact: Sarah Leary 206-987-2106 sarah.leary@seattlechildrens.org Principal Investigator: Sarah Leary Less << |
NCT02420574 | Helminthiasis | Not Applicable | Completed | - | - |
NCT03539731 | Healthy Subject ... More >> Intracranial Neoplasm Recurrent Glioblastoma Less << | Phase 1 | Recruiting | April 23, 2020 | United States, California ... More >> Stanford University, School of Medicine Recruiting Palo Alto, California, United States, 94304 Contact: Hari Priya M. Yerraballa 650-724-9363 yhpriya@stanford.edu Principal Investigator: Sanjiv Gambhir Less << |
NCT01905423 | - | Completed | - | - | |
NCT01905423 | - | Completed | - | Indonesia ... More >> University of Indonesia, Department of Parasitology Jakarta, Java, Indonesia, 10430 Less << | |
NCT01729260 | Newly Diagnosed High-Grade Gli... More >>oma Less << | Phase 1 | Active, not recruiting | September 2020 | United States, Maryland ... More >> The Johs Hopkins Hospital Baltimore, Maryland, United States, 21287 Less << |
NCT01314937 | Malnutrition ... More >>Intestinal Diseases, Parasitic Less << | Phase 4 | Completed | - | Peru ... More >> Asociacion Civil Selva Amazonica Iquitos, Loreto, Peru Less << |
NCT02644291 | Medulloblastoma ... More >> Astrocytoma, Grade III Glioblastoma Anaplastic Astrocytoma Brain Stem Neoplasms, Malignant Oligodendroblastoma Anaplastic Oligodendroglioma Malignant Glioma Less << | Phase 1 | Recruiting | June 2021 | United States, Florida ... More >> Johns Hopkins All Children's Hospital Recruiting Saint Petersburg, Florida, United States, 33701 Contact: Stacie Stapleton, M.D. 727-767-4176 stacie.stapleton@jhmi.edu United States, Maryland Johns Hopkins University School of Medicine Recruiting Baltimore, Maryland, United States, 21231 Contact: Tammy Scott, RN 410-614-5990 SCOTTTA@jhmi.edu Contact: Kenneth J Cohen, MD 410-614-5055 kcohen@jhmi.edu Principal Investigator: Kenneth J Cohen, MD Less << |
NCT03757403 | Idiopathic Pruritus Ani | Phase 2 | Not yet recruiting | January 31, 2020 | United Kingdom ... More >> The Atherstone Surgery Not yet recruiting Atherstone, United Kingdom, CV9 1EU Contact: Jeanette Melrose, MD University Hospitals Bristol NHS Foundation Trust- Location Bristol Royal Infirmary Not yet recruiting Bristol, United Kingdom, IG95LP Contact: Debbie Shipley, MD Kings Medical Centre Buckhurst Hill, United Kingdom, IG95LP Sheepcot Medical Centre Not yet recruiting Watford, United Kingdom, WD25 7NL Contact: Alan Jackson, MD Less << |
NCT03261596 | Hookworm Infections | Phase 4 | Withdrawn(In light of new evid... More >>ence, the decision was made by the sponsor to not proceed.) Less << | December 2017 | Ghana ... More >> Noguchi Memorial Institute for Medical Research - University of Ghana Legon, Accra, Ghana Less << |
NCT02051738 | Healthy | Phase 1 | Completed | - | Belgium ... More >> Merksem, Belgium Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
1.77mL 0.35mL 0.18mL |
8.85mL 1.77mL 0.89mL |
17.71mL 3.54mL 1.77mL |
Tags: DMP 777 | L-694458 | Elastase | Metabolic Enzyme | 157341-41-8
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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