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Chemical Structure| 2306178-56-1 Chemical Structure| 2306178-56-1

Structure of DMX-5804
CAS No.: 2306178-56-1

Chemical Structure| 2306178-56-1

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DMX-5804 is an effective, orally bioavailable, selective MAP4K4 inhibitor with an IC50 value of 3 nM for human MAP4K4 and a pIC50 value of 8.55, it has relatively weaker activity against MINK1/MAP4K6 (pIC50, 8.18) and TNIK/MAP4K7 (pIC50, 7.96).

Synonyms: DMX-5084

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Product Details of DMX-5804

CAS No. :2306178-56-1
Formula : C21H19N3O3
M.W : 361.39
SMILES Code : O=C1C2=C(N(C3=CC=CC=C3)C=C2C4=CC=C(OCCOC)C=C4)N=CN1
Synonyms :
DMX-5084
MDL No. :N/A

Safety of DMX-5804

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of DMX-5804

MAPK
Hippo

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.77mL

0.55mL

0.28mL

13.84mL

2.77mL

1.38mL

27.67mL

5.53mL

2.77mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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