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Chemical Structure| 2823369-81-7 Chemical Structure| 2823369-81-7

Structure of DNA-PK-IN-8
CAS No.: 2823369-81-7

Chemical Structure| 2823369-81-7

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DNA-PK-IN-8 is a highly effective and selective DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 of 0.8 nM. When used in combination with Doxorubicin, this compound exhibits synergistic antiproliferative effects and significantly inhibits tumor growth, especially in the HL-60 tumor model.

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Product Details of DNA-PK-IN-8

CAS No. :2823369-81-7
Formula : C19H22N8O2
M.W : 394.43
SMILES Code : O=C1N(C)C2=CN=C(NC3=CN4C(C=C3C)=NC=N4)N=C2N(C5CCOCC5)C1
MDL No. :N/A

Safety of DNA-PK-IN-8

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of DNA-PK-IN-8

DNA
PI3K-AKT

Isoform Comparison

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.54mL

0.51mL

0.25mL

12.68mL

2.54mL

1.27mL

25.35mL

5.07mL

2.54mL

 

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