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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 1454902-97-6 Chemical Structure| 1454902-97-6

Structure of Elevenostat
CAS No.: 1454902-97-6

Chemical Structure| 1454902-97-6

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Elevenostat is a putative specific inhibitor of HDAC11, which has been shown to deacetylate the transcription factor FoxP3 in T cells.

Synonyms: JB3-22

4.5 *For Research Use Only !

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Product Details of Elevenostat

CAS No. :1454902-97-6
Formula : C16H17N3O4
M.W : 315.32
SMILES Code : O=C(NCC1=CC=C(C(NO)=O)C=C1)NC2=C(OC)C=CC=C2
Synonyms :
JB3-22
MDL No. :N/A
InChI Key :DZHNFBYCLJKJID-UHFFFAOYSA-N
Pubchem ID :71450111

Safety of Elevenostat

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H319-H228
Precautionary Statements:P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313
Class:4.1
UN#:1325
Packing Group:

Related Pathways of Elevenostat

epigenetics

Isoform Comparison

Biological Activity

Description
Elevenostat (JB3-22), a selective HDAC11 inhibitor with an IC50 of 0.235 µM, exhibits anti-multiple myeloma (MM) activity[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.17mL

0.63mL

0.32mL

15.86mL

3.17mL

1.59mL

31.71mL

6.34mL

3.17mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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