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Chemical Structure| 1197194-61-8 Chemical Structure| 1197194-61-8

Structure of Endoxifen E-isomer HCl
CAS No.: 1197194-61-8

Chemical Structure| 1197194-61-8

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Endoxifen E-isomer HCl is a tamoxifen metabolite and potent Selective Estrogen Response Modifier (SERM).

Synonyms: E-Endoxifen hydrochloride; Endoxifen E-isomer hydrochloride

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Product Details of Endoxifen E-isomer HCl

CAS No. :1197194-61-8
Formula : C25H28ClNO2
M.W : 409.95
SMILES Code : OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)/CC)C=C1.[H]Cl
Synonyms :
E-Endoxifen hydrochloride; Endoxifen E-isomer hydrochloride
MDL No. :MFCD29924733

Safety of Endoxifen E-isomer HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
The E-isomer of Endoxifen hydrochloride (E-Endoxifen hydrochloride), known as an impurity in the Z-isomer of Endoxifen, also exhibits antiestrogenic properties[1].[2].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.20mL

2.44mL

1.22mL

24.39mL

4.88mL

2.44mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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