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Chemical Structure| 59989-18-3 Chemical Structure| 59989-18-3

Structure of Eniluracil
CAS No.: 59989-18-3

Chemical Structure| 59989-18-3

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Eniluracil is an orally active dihydropyrimidine dehydrogenase (DPD) inhibitor that irreversibly inhibits DPD, significantly enhancing the oral bioavailability of 5-fluorouracil (5-FU). Eniluracil also serves as a click chemistry reagent in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc), applicable in research on combination cancer therapy with 5-FU.

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Product Details of Eniluracil

CAS No. :59989-18-3
Formula : C6H4N2O2
M.W : 136.11
SMILES Code : O=C1NC(C(C#C)=CN1)=O
InChI Key :JOZGNYDSEBIJDH-UHFFFAOYSA-N
Pubchem ID :43157

Safety of Eniluracil

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00827580 Breast Cancer|Colon Cancer PHASE1 TERMINATED 2025-09-09 Clinical Trials Research Unit,... More >> West Virginia University, Morgantown, West Virginia, 226506, United States Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

7.35mL

1.47mL

0.73mL

36.73mL

7.35mL

3.67mL

73.47mL

14.69mL

7.35mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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