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Chemical Structure| 1621519-26-3 Chemical Structure| 1621519-26-3

Structure of Envonalkib
CAS No.: 1621519-26-3

Chemical Structure| 1621519-26-3

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Synonyms: TQ-B3139; CT-71

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Product Details of Envonalkib

CAS No. :1621519-26-3
Formula : C24H26Cl2FN5O2
M.W : 506.40
SMILES Code : NC1=C(O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C)C=C(C3=C(OC)C=C(N4[C@@H](C)CNCC4)N=C3)C=N1
Synonyms :
TQ-B3139; CT-71
MDL No. :N/A
InChI Key :BVGDAZBTIVRTGO-UONOGXRCSA-N
Pubchem ID :76899983

Safety of Envonalkib

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of Envonalkib

RTK

Isoform Comparison

Biological Activity

Description
Envonalkib is a potent and orally active ALK inhibitor, with IC50 values of 1.96 nM for wild-type ALK, and 35.1 nM and 61.3 nM for the L1196M and G1269S-ALK mutations, respectively. It is investigated for use in non-small cell lung cancer research[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.97mL

0.39mL

0.20mL

9.87mL

1.97mL

0.99mL

19.75mL

3.95mL

1.97mL

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