Structure of Evolocumab
CAS No.: 1256937-27-5
*Storage: {[sel_prStorage]}
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Evolocumab is a humanized IgG2 monoclonal antibody that prevents PCSK9 from binding to LDL receptors. Evolocumab has potential for research on hypercholesterolemia.
Synonyms: AMG 145
4.5
*For Research Use Only !
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Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 1256937-27-5 |
M.W : | 141.8 kDa |
SMILES Code : | NONE |
Synonyms : |
AMG 145
|
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H302-H315-H319 |
Precautionary Statements: | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT05697185 | Ischemic Stroke, Acute | PHASE4 | UNKNOWN | 2024-12-01 | - |
NCT03791593 | Heart Failure With Reduced Eje... More >>ction Fraction Less << | PHASE2 | COMPLETED | 2022-07-20 | Hospital Universitari Germans ... More >>Trias i Pujol, Badalona, Barcelona, 08916, Spain|Hospital Universitario Virgen del Rocío, Sevilla, 41013, Spain|Hospital Clínico de Valencia, Valencia, 46010, Spain Less << |
NCT05152888 | Stable Coronary Disease | PHASE4 | RECRUITING | 2025-12-31 | Brigham and Women's Hospital, ... More >>Boston, Massachusetts, 02115, United States Less << |
NCT02948777 | Type 2 Diabetes Mellitus | PHASE4 | COMPLETED | 2025-06-18 | Helsinki University Hospital, ... More >>Biomedicum 2U, Helsinki, Finland Less << |
NCT05579418 | STEMI|Dyslipidemias | PHASE4 | UNKNOWN | 2024-10-30 | - |
NCT03500302 | Human Immunodeficiency Virus|C... More >>oronary Artery Disease Less << | PHASE2 | COMPLETED | 2019-11-30 | Johns Hopkins University, Balt... More >>imore, Maryland, 21205, United States Less << |
NCT03080935 | Dyslipidemia | PHASE3 | TERMINATED | 2022-03-04 | Algemeen Stedelijk Ziekenhuis ... More >>Aalst, Aalst, 9300, Belgium|Onze Lieve Vrouw Ziekenhuis Aalst, Aalst, 9300, Belgium|Ziekenhuis Netwerk Antwerpen Middelheim, Antwerpen, 2020, Belgium|Ziekenhuis Netwerk Antwerpen Stuivenberg, Antwerpen, 2060, Belgium|Imelda Ziekenhuis vzw, Bonheiden, 2820, Belgium|Centre Hospitalier Universitaire Brugmann, Brussels, 1020, Belgium|Cliniques universitaires de Bruxelles Hopital Erasme, Brussels, 1070, Belgium|Universite Catholique de Louvain Cliniques Universitaires Saint Luc, Bruxelles, 1200, Belgium|Algemeen Ziekenhuis Sint Lucas, Gent, 9000, Belgium|Universitair Ziekenhuis Gent, Gent, 9000, Belgium|Medif sprl, Gozee, 6534, Belgium|Centre Hospitalier Universitaire de Tivoli, La Louvi?¨re, 7100, Belgium|Centres Hospitaliers Jolimont - Hopital de Jolimont, La Louvi?¨re, 7100, Belgium|Centre Hospitalier Universitaire de Liege - Sart Tilman, Liege, 4000, Belgium|Centre Hospitalier Regional de la Citadelle, Li?¨ge, 4000, Belgium|Algemeen Ziekenhuis Turnhout, Turnhout, 2300, Belgium|Aalborg Hospital, Aalborg, 9000, Denmark|Center for Clinical and Basic Research Aalborg, Aalborg, 9000, Denmark|Aarhus Universitetshospital, Aarhus N, 8200, Denmark|Centre for Clinical and Basic Research Ballerup, Ballerup, 2750, Denmark|Sydvestjysk Sygehus, Esbjerg, 6700, Denmark|Frederiksberg/Bispebjerg Hospitaler, Frederiksberg, 2000, Denmark|Glostrup Hospital, Glostrup, 2600, Denmark|Hvidovre Hospital, Hvidovre, 2650, Denmark|Amager Hospital, Kobenhavn S, 2300, Denmark|Odense Universitetssygehus, Odense, 5000, Denmark|Sjaellands Universitetshospital, Roskilde, Roskilde, 4000, Denmark|Svendborg Sygehus, Svendborg, 5700, Denmark|Center for Clinical and Basic Research Vejle, Vejle, 7100, Denmark|Regionshospitalet Viborg, Viborg, 8800, Denmark|Centre Hospitalier Regional Universitaire de Besancon, Hopital Jean Minjoz, Besancon cedex, 25030, France|Centre Hospitalier R??gional Universitaire de Tours - H?′pital Trousseau, Chambray les Tours, 37170, France|Hopital Louis Pasteur, Le Coudray, 28630, France|Centre Hospitalier Regional Universitaire de Montpellier - Hopital Arnaud de Villeneuve, Montpellier cedex 05, 34295, France|Centre Hospitalier Universitaire de Nantes - Hopital Guillaume et Rene Laennec, Nantes Cedex 1, 44093, France|Nouvelles Cliniques Nantaises, Nantes Cedex 2, 44202, France|Centre Hospitalier Universitaire de Nice - Hopital Pasteur, Nice, 06000, France|Hopital Lariboisiere, Paris, 75010, France|Hopital Pitie-Salpetriere, Paris, 75013, France|Centre Hospitalier de Pau - Hopital Francois Mitterrand, Pau, 64000, France|Centre Hospitalier Universitaire de Reims - Hopital Robert Debre, Reims, 51100, France|Centre Hospitalier Universitaire de Toulouse - Hopital Rangueil, Toulouse Cedex 9, 31059, France|Centre Hospitalier Intercommunal Haute Saone, Vesoul, 70014, France|Universitaets-Herzzentrum Freiburg - Bad Krozingen, Bad Krozingen, 79189, Germany|Klinische Forschung Berlin GbR, Berlin, 10787, Germany|Vivantes Klinikum Neuk??lln, Berlin, 12351, Germany|Deutsches Rotes Kreuz Kliniken Berlin K??penick, Berlin, 12559, Germany|Deutsches Herzzentrum Berlin, Berlin, 13353, Germany|Sankt-Johannes-Hospital, Dortmund, 44137, Germany|Gesellschaft fur Wissens und Technologietransfer der Technischen Uni Dresden, Dresden, 01307, Germany|Ambulantes Herzzentrum Kassel, Kassel, 34121, Germany|Universit?¤tsklinikum K??ln, K??ln, 50937, Germany|Otto von Guericke Universit?¤t Magdeburg, Magdeburg, 39120, Germany|Johannes Gutenberg Universit?¤t Mainz, Mainz, 55131, Germany|Herz-Gef?¤??-Zentrum Nymphenburg am Klinikum Dritter Orden, M??nchen, 80333, Germany|Deutsches Herzzentrum M??nchen des Freistaates Bayern, M??nchen, 80636, Germany|Robert Bosch Krankenhaus, Stuttgart, 70376, Germany|Universit?¤tsklinikum Ulm, Ulm, 89081, Germany|Forschungszentrum Ruhr, Witten, 58455, Germany|Helios Universit?¤tsklinikum Wuppertal, Wuppertal, 42117, Germany|Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, 24127, Italy|Azienda Ospedaliero Universitaria Careggi, Firenze, 50139, Italy|Centro Cardiologico Monzino, Milano, 20138, Italy|Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, 20162, Italy|Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello, Palermo, 90146, Italy|Fondazione IRCCS Policlinico San Matteo, Pavia, 27100, Italy|Azienda Ospedaliera di Perugia Ospedale Santa Maria della Misericordia, Perugia, 06129, Italy|Fondazione Toscana Gabriele Monasterio, Stabilimento Ospedaliero di Pisa, Pisa, 56124, Italy|Azienda Ospedaliera Universitaria Senese Policlinico Le Scotte, Siena, 53100, Italy|Hospital Garcia de Orta, EPE, Almada, 2801-951, Portugal|Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, 3000-075, Portugal|Centro Hospitalar Cova da Beira, EPE - Hospital Pero da Covilha, Covilha, 6200-251, Portugal|Hospital Cuf Infante Santo, Lisboa, 1350-352, Portugal|Centro Hospitalar de Lisboa Ocidental, EPE - Hospital Sao Francisco Xavier, Lisboa, 1449-005, Portugal|Centro Hospitalar de Setubal EPE Hospital de Sao Bernardo, Setubal, 2910-446, Portugal|Falu Lasarett, Falun, 791 82, Sweden|Helsingborgs Lasarett, Helsingborg, 252 47, Sweden|L?¤nssjukhuset Ryhov, J??nk??ping, 551 85, Sweden|Sunderby Sjukhus, Lulea, 971 80, Sweden|Skanes Universitetssjukhus, Lund, 221 85, Sweden|Capio Citykliniken, Lund, 222 21, Sweden|Universitetssjukhuset ?-rebro, Orebro, 701 85, Sweden|Ostersunds sjukhus, Ostersund, 831 83, Sweden|Akardo MedSite, Stockholm, 117 27, Sweden|Norrlands Universitetssjukhus, Umea, 901 85, Sweden Less << |
NCT04087915 | Dyslipidemia|High Risk Coronar... More >>y Artery Disease Less << | UNKNOWN | 2021-12-31 | Beijing Anzhen Hospital, Capit... More >>al Medical University, Beijing, Beijing, 100029, China Less << | |
NCT05418166 | Acute Coronary Syndrome | UNKNOWN | 2022-09-01 | the first affiliated hospital ... More >>of Harbin Medical University, Harbin, Heilongjiang, 150000, China Less << | |
NCT03247972 | Peripheral Arterial Disease | TERMINATED | 2019-10-01 | Inova Fairfax Hospital, Falls ... More >>Church, Virginia, 22042, United States Less << | |
NCT03331666 | Familial Hypercholesterolemia | PHASE4 | TERMINATED | 2020-02-04 | Columbia University Medical Ce... More >>nter, New York, New York, 10032, United States Less << |
NCT03944577 | Heart Transplant | PHASE2 | COMPLETED | 2023-03-28 | University of Nebraska Medical... More >> Center, Omaha, Nebraska, 68198, United States Less << |
NCT04665830 | Kideny Transplant Recipients W... More >>ith High Cardiovascular Risk Score Less << | PHASE3 | COMPLETED | 2020-05-01 | OTC, MOH , Kuwait, Kuwait, Kuw... More >>ait, Kuwait Less << |
NCT06140095 | Acute Metabolic Effects of Evo... More >>locumab and Atorvastatin Less << | EARLY_PHASE1 | NOT_YET_RECRUITING | 2025-12-25 | - |
NCT04100434 | Acute Coronary Syndrome|Propro... More >>tein Convertase Subtilisin/Kexin Type 9 Inhibitor Less << | PHASE4 | UNKNOWN | 2023-06-01 | Tianjin Chest Hospital,, Tianj... More >>in, 300222, China Less << |
NCT06231459 | Hypercholesterolemia, Familial | PHASE4 | COMPLETED | 2020-12-31 | National Medical Center "20 de... More >> Noviembre", ISSSTE, Mexico City, 03100, Mexico Less << |
NCT04313270 | Hypercholesterolemia, Familial | RECRUITING | 2025-12-01 | Matteo Di Minno, Napoli, 80131... More >>, Italy Less << | |
NCT04937413 | Malignant Glioma|Glioblastoma | EARLY_PHASE1 | COMPLETED | 2023-10-12 | Duke University Medical Center... More >>, Durham, North Carolina, 27710, United States Less << |
NCT04539223 | Carotid Artery Stenosis|Asympt... More >>omatic Carotid Artery Stenosis Less << | PHASE4 | UNKNOWN | 2025-05-22 | North York Diagnostic and Card... More >>iac Centre, North York, Ontario, M6B 3H7, Canada|East Toronto Vascular Clinic, Toronto, Ontario, M4L3Y3, Canada|St. Michael's Hospital, Toronto, Ontario, Canada Less << |
Tags: Evolocumab | AMG 145 | PCSK9 | PCSK9/monoclonal antibody | Human Inhibitory Monoclonal Antibody | Other Inhibitors/Agonists | 1256937-27-5
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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