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Chemical Structure| 197720-53-9 Chemical Structure| 197720-53-9

Structure of Exatecan mesylate dihydrate
CAS No.: 197720-53-9

Chemical Structure| 197720-53-9

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Exatecan mesylate dihydrate (DX-8951) mesylate dihydrate is a DNA topoisomerase I inhibitor (IC50 = 2.2 µM / 0.975 µg/mL) used in cancer research.

Synonyms: DX-8951 mesylate dihydrate

4.5 *For Research Use Only !

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Product Details of Exatecan mesylate dihydrate

CAS No. :197720-53-9
Formula : C25H28FN3O8S
M.W : 549.57
SMILES Code : O=C1[C@@](CC)(OS(C)(=O)=O)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O.[H]O[H].[H]O[H]
Synonyms :
DX-8951 mesylate dihydrate
MDL No. :MFCD23102386
InChI Key :FXQZOHBMBQTBMJ-MWPGLPCQSA-N
Pubchem ID :151114

Safety of Exatecan mesylate dihydrate

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P501-P270-P264-P301+P310+P330-P405
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Exatecan mesylate dihydrate

DNA

Isoform Comparison

Biological Activity

Description
Exatecan mesylate dihydrate (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), suitable for application in cancer research [1][2][3].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.82mL

0.36mL

0.18mL

9.10mL

1.82mL

0.91mL

18.20mL

3.64mL

1.82mL

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