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Chemical Structure| 2304465-89-0 Chemical Structure| 2304465-89-0

Structure of F5446
CAS No.: 2304465-89-0

Chemical Structure| 2304465-89-0

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F5446 is an inhibitor of SUV39H1 methyltransferase, inducing dose-dependent death of human colon cancer cells.

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Product Details of F5446

CAS No. :2304465-89-0
Formula : C26H17ClN2O8S
M.W : 552.94
SMILES Code : O=C(C1=CNC2=C1C3=C(N(S(=O)(C4=CC=C(Cl)C=C4)=O)C(C(OC)=O)=C3)C(C2=O)=O)OCC5=CC=CC=C5

Safety of F5446

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of F5446

epigenetics

Isoform Comparison

Biological Activity

Description
F5446 is an inhibitor of SUV39H1 methyltransferase. It induces cell death in human colon carcinoma cells in a dose-dependent manner[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.81mL

0.36mL

0.18mL

9.04mL

1.81mL

0.90mL

18.09mL

3.62mL

1.81mL

Dissolving Methods
The prepared working fluid is recommended to be prepared now and used up as soon as possible in a short period of time. The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1

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