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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 57653-26-6 Chemical Structure| 57653-26-6

Structure of Fenobam
CAS No.: 57653-26-6

Chemical Structure| 57653-26-6

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Fenobam is a selective, orally active, blood-brain barrier-penetrating mGluR5 antagonist that acts at the allosteric modulation site (with Kd values of 54 nM and 31 nM at rat and human recombinant mGlu5 receptors, respectively). Fenobam has inverse agonist activity, blocking mGlu5 receptor activity with an IC50 of 84 nM. Fenobam has anxiolytic activity.

4.5 *For Research Use Only !

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Product Details of Fenobam

CAS No. :57653-26-6
Formula : C11H11ClN4O2
M.W : 266.68
SMILES Code : O=C(NC1=NC(CN1C)=O)NC2=CC=CC(Cl)=C2
MDL No. :MFCD00868019

Safety of Fenobam

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H300-H315-H319-H335
Precautionary Statements:P233-P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P330-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of Fenobam

GPCR

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01981395 Hyperalgesia ... More >>Allodynia Less << Phase 1 Completed - United States, Missouri ... More >> Washington University School of Medicine St. Louis, Missouri, United States, 63110 Less <<
NCT01806415 Healthy Phase 1 Completed - United States, Missouri ... More >> Washington University School Of Medicine St. Louis, Missouri, United States, 63110 Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.75mL

0.75mL

0.37mL

18.75mL

3.75mL

1.87mL

37.50mL

7.50mL

3.75mL

References

 

Historical Records

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