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Chemical Structure| 1702864-11-6 Chemical Structure| 1702864-11-6

Structure of FF-10101 succinate
CAS No.: 1702864-11-6

Chemical Structure| 1702864-11-6

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FF-10101 succinate is an irreversible FLT3 inhibitor used for the treatment of acute myeloid leukemia (AML).It inhibits FLT3 activity by forming a covalent bond with cysteine 695 (C695) in the active site of the FLT3 tyrosine kinase.

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Product Details of FF-10101 succinate

CAS No. :1702864-11-6
Formula : C33H44N8O6
M.W : 648.75
SMILES Code : O=C(N([C@@H](C)C(NCCCC#CC1=CN=C(NC2=CC=C(C#N)C=C2)N=C1NCCC)=O)C)/C=C/CN(C)C.OC(CCC(O)=O)=O
MDL No. :MFCD31630737
InChI Key :BBKTUZZYTYYDAM-CQELKUSOSA-N
Pubchem ID :133053567

Safety of FF-10101 succinate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of FF-10101 succinate

RTK

Isoform Comparison

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1 mM

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1.54mL

0.31mL

0.15mL

7.71mL

1.54mL

0.77mL

15.41mL

3.08mL

1.54mL

 

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