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Chemical Structure| 1802998-75-9 Chemical Structure| 1802998-75-9

Structure of Filgotinib maleate
CAS No.: 1802998-75-9

Chemical Structure| 1802998-75-9

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Filgotinib maleate (GLPG0634 maleate) is a selective, orally active JAK1 inhibitor with IC50 values of 10 nM for JAK1, 28 nM for JAK2, 810 nM for JAK3, and 116 nM for TYK2. It possesses anti-inflammatory and antiviral activities.

Synonyms: GLPG0634 maleate

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Product Details of Filgotinib maleate

CAS No. :1802998-75-9
Formula : C25H27N5O7S
M.W : 541.58
SMILES Code : O=C(C1CC1)NC2=NN3C(C4=CC=C(CN(CC5)CCS5(=O)=O)C=C4)=CC=CC3=N2.O=C(O)/C=C\C(O)=O
Synonyms :
GLPG0634 maleate
MDL No. :MFCD34184747

Safety of Filgotinib maleate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of Filgotinib maleate

epigenetics
RTK
JAK-STAT

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.85mL

0.37mL

0.18mL

9.23mL

1.85mL

0.92mL

18.46mL

3.69mL

1.85mL

 

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