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Chemical Structure| 147359-76-0 Chemical Structure| 147359-76-0

Structure of Flibanserin HCl
CAS No.: 147359-76-0

Chemical Structure| 147359-76-0

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Flibanserin hydrochloride is an orally active 5-HT1A receptor agonist and 5-HT2A receptor antagonist with antidepressant and anxiolytic effects. It can bind to dopamine D4 receptors (Ki=4-24 nM) and is suitable for research on hypoactive sexual desire.

Synonyms: BIMT-17 hydrochloride; BIMT-17BS hydrochloride

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Product Details of Flibanserin HCl

CAS No. :147359-76-0
Formula : C20H22ClF3N4O
M.W : 426.86
SMILES Code : O=C1N(CCN2CCN(C3=CC=CC(C(F)(F)F)=C3)CC2)C4=CC=CC=C4N1.[H]Cl
Synonyms :
BIMT-17 hydrochloride; BIMT-17BS hydrochloride
MDL No. :MFCD29058559
InChI Key :XGAGFLQFMFCIHZ-UHFFFAOYSA-N
Pubchem ID :9845393

Safety of Flibanserin HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Description
Flibanserin hydrochloride (BIMT-17; BIMT-17BS) is an orally active antagonist of serotonin 5-HT2A receptors and an agonist of 5-HT1A receptors, displaying Ki values of 49 nM and 1 nM, respectively. This compound also attaches to dopamine D4 receptors, presenting a Ki value ranging from 4 to 24 nM. Flibanserin hydrochloride is noted for its anti-depression and anti-anxiety properties and is utilized in the study of hypoactive sexual desire disorder (HSDD)[1].[5].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.34mL

0.47mL

0.23mL

11.71mL

2.34mL

1.17mL

23.43mL

4.69mL

2.34mL

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