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Chemical Structure| 86393-33-1 Chemical Structure| 86393-33-1
Chemical Structure| 86393-33-1

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Fluoroquinolonic acid acts as an intermediate during the synthesis of ciprofloxacin HCl which is a broad-spectrum antibacterial agent.

Synonyms: Ciprofloxacin Impurity A; Q-Acid

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Product Details of Fluoroquinolonic Acid

CAS No. :86393-33-1
Formula : C13H9ClFNO3
M.W : 281.67
SMILES Code : O=C(C1=CN(C2CC2)C3=C(C=C(F)C(Cl)=C3)C1=O)O
Synonyms :
Ciprofloxacin Impurity A; Q-Acid
MDL No. :MFCD00792458
InChI Key :ISPVACVJFUIDPD-UHFFFAOYSA-N
Pubchem ID :483180

Safety of Fluoroquinolonic Acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H412
Precautionary Statements:P501-P273-P270-P264-P301+P312+P330

Application In Synthesis of Fluoroquinolonic Acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 86393-33-1 ]

[ 86393-33-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 86393-33-1 ]
  • [ 85803-49-2 ]
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-methyl-3-(thien-3-yl)-1-piperazinyl]-3-quinolinecarboxylic acid [ No CAS ]
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(thien-3-yl)-1-piperazinyl]-3-quinolinecarboxylic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
With pyridine; EXAMPLE 66 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-methyl-3-(3-thienyl)-1-piperazinyl]-3-quinolinecarboxylic acid A mixture of 1.124 g of 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 2.688 g of 3-thienylpiperazine and 12 ml of pyridine was reacted as described in Example 60, giving 900 mg of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(3-thienyl)-1-piperazinyl]-3-quinolinecarboxylic acid. A 207 mg portion of the above compound was then reacted as described in Example 55, giving 150 mg of the desired product, mp 230 C.
 

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