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Chemical Structure| 1350456-56-2 Chemical Structure| 1350456-56-2

Structure of Fmoc-Val-Cit-PAB-MMAE
CAS No.: 1350456-56-2

Chemical Structure| 1350456-56-2

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Fmoc-Val-Cit-PAB-MMAE consists the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE), Fmoc-Val-Cit-PAB-MMAE is an antibody drug conjugate.

Synonyms: Fmoc-Val-Cit-PAB-MMAE

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Product Details of Fmoc-Val-Cit-PAB-MMAE

CAS No. :1350456-56-2
Formula : C73H104N10O14
M.W : 1345.67
SMILES Code : O=C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@]([C@@H](C)CC)([H])[C@H](OC)CC(N(CCC2)[C@]2([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C3=CC=CC=C3)O)=O)=O)=O)=O)=O)C=C1)=O)=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
Synonyms :
Fmoc-Val-Cit-PAB-MMAE
MDL No. :MFCD30377196
InChI Key :RHQGFVOXIOMBMC-UUMMFNFXSA-N
Pubchem ID :118986648

Safety of Fmoc-Val-Cit-PAB-MMAE

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Related Pathways of Fmoc-Val-Cit-PAB-MMAE

cytoskeleton

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

0.74mL

0.15mL

0.07mL

3.72mL

0.74mL

0.37mL

7.43mL

1.49mL

0.74mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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