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Chemical Structure| 26130-02-9 Chemical Structure| 26130-02-9

Structure of Frentizole
CAS No.: 26130-02-9

Chemical Structure| 26130-02-9

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Frentizole, an immunosuppressive drug, is an inhibitor of the Aβ-ABAD interaction.

Synonyms: Frentizol

4.5 *For Research Use Only !

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Product Details of Frentizole

CAS No. :26130-02-9
Formula : C15H13N3O2S
M.W : 299.35
SMILES Code : O=C(NC1=CC=CC=C1)NC2=NC3=CC=C(OC)C=C3S2
Synonyms :
Frentizol
MDL No. :MFCD00030234
InChI Key :JHBWYQRKOUBPCA-UHFFFAOYSA-N
Pubchem ID :33334

Safety of Frentizole

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319-H413
Precautionary Statements:P264-P270-P273-P280-P301+P312+P330-P305+P351+P338-P337+P313-P501

Isoform Comparison

Biological Activity

Description
Frentizole is an immunosuppressant approved by the FDA and inhibits the interaction between Aβ and ABAD with an IC50 of 200 µM, finding use in research on rheumatoid arthritis and systemic lupus erythematosus[1].[2].[3].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.34mL

0.67mL

0.33mL

16.70mL

3.34mL

1.67mL

33.41mL

6.68mL

3.34mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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