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Chemical Structure| 67469-75-4 Chemical Structure| 67469-75-4

Structure of GBR 12783 2HCl
CAS No.: 67469-75-4

Chemical Structure| 67469-75-4

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GBR 12783 is a selective dopamine reuptake inhibitor that effectively inhibits the uptake of [3H] dopamine in the striatal synaptosomes of rats and mice (IC50 values of 1.8 nM and 1.2 nM, respectively). Additionally, it can enhance memory in rats and increase acetylcholine release in the hippocampal pathway, suitable for research on neurodegenerative diseases and memory disorders.

Synonyms: GBR 12783 dihydrochloride

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Product Details of GBR 12783 2HCl

CAS No. :67469-75-4
Formula : C28H34Cl2N2O
M.W : 485.49
SMILES Code : [H]Cl.[H]Cl.N1(CCOC(C2=CC=CC=C2)C3=CC=CC=C3)CCN(C/C=C/C4=CC=CC=C4)CC1
Synonyms :
GBR 12783 dihydrochloride
InChI Key :HJDXBLLTRMCYNC-JFXLULTRSA-N
Pubchem ID :24744862

Safety of GBR 12783 2HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of GBR 12783 2HCl

GPCR

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1 mM

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2.06mL

0.41mL

0.21mL

10.30mL

2.06mL

1.03mL

20.60mL

4.12mL

2.06mL

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