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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 905281-76-7 Chemical Structure| 905281-76-7

Structure of GDC-0879
CAS No.: 905281-76-7

Chemical Structure| 905281-76-7

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GDC-0879 is a potent, and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well, displaying no inhibition known to other protein kinases.

Synonyms: AR-00341677

4.5 *For Research Use Only !

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Product Details of GDC-0879

CAS No. :905281-76-7
Formula : C19H18N4O2
M.W : 334.37
SMILES Code : O/N=C1C(C=CC(C2=CN(CCO)N=C2C3=CC=NC=C3)=C4)=C4CC/1
Synonyms :
AR-00341677
MDL No. :MFCD16875916

Safety of GDC-0879

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H228-H302-H317-H319-H341-H351
Precautionary Statements:P280-P210-P240-P264-P270-P301+P310-P330-P370+P378-P403+P233-P405-P501
Class:4.1
UN#:1325
Packing Group:

Related Pathways of GDC-0879

MAPK

Isoform Comparison

Biological Activity

Target
  • B-Raf

    B-Raf, IC50:0.13 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.99mL

0.60mL

0.30mL

14.95mL

2.99mL

1.50mL

29.91mL

5.98mL

2.99mL

References

 

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