Structure of GF 15
CAS No.: 888042-13-5
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.
4.5
*For Research Use Only !
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CAS No. : | 888042-13-5 |
Formula : | C23H21ClO6 |
M.W : | 428.86 |
SMILES Code : | O=C1[C@]2(C(OCC3=CC=CC=C3)=CC(C[C@H]2C)=O)OC4=C(Cl)C(OC)=CC(OC)=C14 |
MDL No. : | MFCD28963906 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT02995616 | Stroke | Not Applicable | Recruiting | December 2018 | Belgium ... More >> St. Ursula Rehabilitation Centre (Jessa Hospital) Recruiting Herk-de-Stad, Limburg, Belgium, 3540 Contact: Marc Michielsen, PT 0032 13 55 06 57 marc.michielsen@jessazh.be Contact: Stieven Henderix, PT 0032 13 55 06 00 stieven.henderix@jessazh.be Less << |
NCT03708835 | Stroke | Not Applicable | Active, not recruiting | December 20, 2018 | Turkey ... More >> Yasemin Demi̇r Avci̇ Antalya, Turkey, 07058 Less << |
NCT02827201 | Metastatic Pancreatic Cancer | Phase 2 | Active, not recruiting | November 2018 | France ... More >> Clinique Privée Claude Bernard Albi, France CH Blois, France Clinique Tivoli Ducos Bordeaux, France Hôpital Duchenne Boulogne sur Mer, France CH Pierre Oudot Bourgoin-Jallieu, France Centre François Baclesse Caen, France CHR côte de Nacre Caen, France Centre Hospitalier Sud Francilien Corbeil Essonnes, France Centre GF Leclerc Dijon, France CH de la Dracénie Draguignan, France Ch Jacques Monod Flers, France CH Frejus, France CHU Le Kremlin Bicetre, France CH Le Mans, France CHU Limoges, France Clinique Chenieux Limoges, France CH Longjumeau -, France CH Pierre Benite Lyon, France Hopital Europeen Marseille Marseille, France, 13331 H Layné Mont-de-Marsan, France HEGP Paris, France, 75020 Hôpital La Pitié Salpêtrière Paris, France, 75651 Hôpital Cochin Paris, France CH St Jean Perpignan, France Hôpital Haut Lévèque Pessac, France Centre Cario - Hpca Saint Brieuc Plérin, France Hôpitaux Drome Nord Romans Sur Isere, France CHU Rouen, France CHP Saint Grégoire, France Clinique Privée Strasbourg, France Hopitaux Du Leman Thonon Les Bains, France Clinique Pasteur Groupe ONCORAD GARONNE Toulouse, France Clinique Privée Pasteur Toulouse, France Clinique Privée Saint Jean Toulouse, France Clinique St Jean Languedoc Toulouse, France Gustave Roussy Villejuif, France, 94805 Hôpital Paul Brousse Villejuif, France Less << |
NCT02538965 | - | Active, not recruiting | - | - | |
NCT03034330 | Stroke | Not Applicable | Recruiting | July 2019 | Hong Kong ... More >> Sau Po Center on Ageing HKU Recruiting Hong Kong, Hong Kong Contact: Clio Cheng, MSocSc (852)28315206 clioc@hku.hk Contact: Joyce Fu, MSW (852)28315213 joycefu@hku.hk Less << |
NCT02538965 | Leukemia, Myeloid | Phase 2 | Active, not recruiting | July 13, 2022 | - |
NCT02429661 | Emotional Wellbeing ... More >> Social Wellbeing Physical Wellbeing Less << | Not Applicable | Completed | - | United States, California ... More >> CorStone Mill Valley, California, United States, 94941 Less << |
NCT00362089 | Overweight Ob... More >>esity Less << | Not Applicable | Completed | - | Germany ... More >> Else Kröner-Fresenius-Zentrum für Ernährungsmedizin, Technische Universität München Munich, Germany, 81675 Less << |
NCT02233517 | Aggression An... More >>ger Posttraumatic Stress Disorder Less << | Not Applicable | Completed | - | United States, North Carolina ... More >> Durham VA Medical Center, Durham, NC Durham, North Carolina, United States, 27705 Less << |
NCT03332966 | - | Not yet recruiting | December 31, 2023 | - | |
NCT03664154 | Feeding Behavior ... More >> Preterm Infant Stress Mother-Infant Interaction Less << | Not Applicable | Recruiting | July 2019 | United States, Virginia ... More >> Virginia Commonwealth University Recruiting Richmond, Virginia, United States, 23298 Less << |
NCT02891499 | Displacement of Other Bone Dev... More >>ices, Implants and Grafts Mechanical Complication of Other Bone Devices, Implants and Grafts Less << | Not Applicable | Completed | - | - |
NCT02477735 | - | Unknown | December 2017 | Israel ... More >> "DANA" children's hospital Not yet recruiting Tel-Aviv, Israel Less << | |
NCT03448159 | Stroke Cerebr... More >>ovascular Accident Cerebral Infarction Brain Infarction Brain Ischemia Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Less << | Phase 2 | Not yet recruiting | December 31, 2020 | Canada, Alberta ... More >> University of Calgary Not yet recruiting Calgary, Alberta, Canada, T2N 1N4 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: Sean Dukelow, MD Canada, British Columbia University of British Columbia & GF Strong Centre Not yet recruiting Vancouver, British Columbia, Canada, V5Z 2G9 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: Janice Eng, PhD Canada, Newfoundland and Labrador Memorial University of Newfoundland Not yet recruiting St. John's, Newfoundland and Labrador, Canada, A1B 3X9 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: Michelle Ploughman, PhD Canada, Nova Scotia Dalhousie University Not yet recruiting Halifax, Nova Scotia, Canada, B3H 4R2 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: Marilyn Mackay-Lyons, PhD Canada, Ontario Parkwood Institute Not yet recruiting London, Ontario, Canada, N6C 0A7 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: Robert Teasell, MD Sunnybrook Health Sciences Centre Not yet recruiting Toronto, Ontario, Canada, M4N 3M5 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: Sandra Black, MD Toronto Rehabilitation Institute - University Health Network Not yet recruiting Toronto, Ontario, Canada, M5G 2A2 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: Mark Bayley, MD University of Waterloo Not yet recruiting Waterloo, Ontario, Canada, N2L 3G1 Contact: Farrell Leibovitch 416-480-6100 ext 7548 farrell@canadianstroke.ca Principal Investigator: William McIlroy, PhD Sub-Investigator: Robyn Ibey, PhD Less << |
NCT02995265 | Conditions | Not Applicable | Recruiting | December 31, 2020 | Canada, British Columbia ... More >> GF Strong Rehab Centre Recruiting Vancouver, British Columbia, Canada, V5Z 2G9 Contact: Chihya Hung, MScPT 604-714-4108 chihya.hung@ubc.ca Less << |
NCT01740635 | Difficulty Walking | Not Applicable | Completed | - | Canada, British Columbia ... More >> GF Strong Rehabilitation Centre Vancouver, British Columbia, Canada, V5Z 2G9 Canada, Manitoba University of Manitoba Winnipeg, Manitoba, Canada, R3E 0T6 Less << |
NCT03693196 | Peri-implant Mucositis ... More >> Peri-Implantitis Less << | Not Applicable | Completed | - | - |
NCT01923883 | EUS-FNA Cytod... More >>iagnosis Less << | Not Applicable | Unknown | June 2014 | Korea, Republic of ... More >> Asan Medical Center Recruiting Seoul, Korea, Republic of, 138-736 Contact: Do Hyun Park, MD, PhD +82230103194 dhpark@amc.seoul.kr Less << |
NCT03325049 | Family Health | Not Applicable | Recruiting | November 1, 2019 | Sweden ... More >> Linköping university Recruiting Linköping, Sweden, S-58183 Contact: Susanna Ågren, PhD susanna.agren@liu.se Contact: Mona Ahlberg, PhD student Mona.K.Ahlberg@regionostergotland.se Less << |
NCT02031068 | Sport-related Concussion ... More >> Concussion Mild Traumatic Brain Injury (MTBI) Less << | Not Applicable | Unknown | February 2016 | Canada, British Columbia ... More >> GF Strong Rehabilitation Centre Recruiting Vancouver, British Columbia, Canada, V5Z 2G9 Contact: Catherine Chan, MPT (604) 734-1313 Catherine.chan2@vch.ca Principal Investigator: Catherine Chan, MPT Less << |
NCT02789098 | ST Elevation Myocardial Infarc... More >>tion Less << | Not Applicable | Recruiting | March 2020 | France ... More >> CHu de Caen Recruiting Caen, Normandie, France, 14000 Contact: Damien LEGALLOIS, MD +33 231065704 Less << |
NCT02696213 | Mobility Scooter Skills Traini... More >>ng Less << | Not Applicable | Recruiting | - | Canada, British Columbia ... More >> GF Strong Rehabilitation Center Recruiting Vancouver, British Columbia, Canada, V5Z 2G9 Contact: Leena Chau 604-718-4108 leena.chau@ubc.ca Less << |
NCT02780739 | Cognitive Ability, General | Not Applicable | Completed | - | United States, Illinois ... More >> University of Illinois at Urbana-Champaign Urbana, Illinois, United States, 61801 Less << |
NCT02882854 | Postoperative Nausea and Vomit... More >>ing Pain, Postoperative Less << | Not Applicable | Unknown | July 2017 | United States, Tennessee ... More >> Vanderbilt University Medical Center Recruiting Nashville, Tennessee, United States, 37212 Principal Investigator: Stephen Harvey, MD Less << |
NCT03319888 | Chronic Kidney Insufficiency ... More >> Sleep Apnea Less << | Not Applicable | Recruiting | May 20, 2020 | Spain ... More >> Jaime Corral Recruiting Cáceres, Spain, 10003 Contact: Jaime Corral, MD 927256204 jcorral@separ.es Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.33mL 0.47mL 0.23mL |
11.66mL 2.33mL 1.17mL |
23.32mL 4.66mL 2.33mL |
Tags: GF 15 | 888042-13-5
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
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