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Chemical Structure| 1351761-44-8 Chemical Structure| 1351761-44-8

Structure of GNE-7915
CAS No.: 1351761-44-8

Chemical Structure| 1351761-44-8

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GNE-7915 is a highly selective and brain-penetrant LRRK2 inhibitor with an IC50 value of 9 nM.

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Product Details of GNE-7915

CAS No. :1351761-44-8
Formula : C19H21F4N5O3
M.W : 443.40
SMILES Code : O=C(C1=CC(OC)=C(NC2=NC=C(C(F)(F)F)C(NCC)=N2)C=C1F)N3CCOCC3
MDL No. :MFCD25977005
InChI Key :XCFLWTZSJYBCPF-UHFFFAOYSA-N
Pubchem ID :58539171

Safety of GNE-7915

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • LRRK2

    LRRK2, IC50:9 nM

    LRRK2, Ki:1 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.26mL

0.45mL

0.23mL

11.28mL

2.26mL

1.13mL

22.55mL

4.51mL

2.26mL

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